Cochrane · systematic review · CD011817
Serum or plasma ferritin concentration as an index of iron deficiency and overload
Garcia-Casal, MN, Pasricha, S-R, Martinez, RX, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Tobacco AddictionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
8
No studies
4
Included studies
NR
No studies 4 · 33.3%Ungraded 0 · 0%Very low 4 · 33.3%Low 4 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Estimates of accuracy of serum ferritin to assess iron deficiency for apparently healthy (all)
Population: :
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Test Accuracy | no estimate extracted | NR | No studies |
Sensitivity | no estimate extracted | 5 studies · 143 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Specificity | no estimate extracted | 5 studies · 207 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Estimates of accuracy of serum ferritin to assess iron deficiency for non‐healthy (*adults)
Population: :
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Test Accuracy | no estimate extracted | NR | No studies |
Sensitivity | no estimate extracted | 63 studies · 1765 participants | Low Downgraded: risk of bias, inconsistency, indirectness |
Specificity | no estimate extracted | 63 studies · 3277 participants | Low Downgraded: risk of bias, inconsistency, indirectness |
Estimates of accuracy of serum ferritin to assess iron deficiency for non‐healthy (*adults): threshold = 30 µg/L
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Test Accuracy | no estimate extracted | NR | No studies |
Sensitivity | no estimate extracted | 9 studies · 203 participants | Low Downgraded: risk of bias, imprecision |
Specificity | no estimate extracted | 9 studies · 309 participants | Low Downgraded: risk of bias, imprecision |
Estimates of accuracy of serum ferritin to assess iron overload (all)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Test Accuracy | no estimate extracted | NR | No studies |
Sensitivity | no estimate extracted | 36 studies · 803 participants | Very low Downgraded: risk of bias, inconsistency, indirectness |
Specificity | no estimate extracted | 36 studies · 1124 participants | Very low Downgraded: risk of bias, inconsistency, indirectness |