Cochrane · systematic review · CD013790
Heated tobacco products for smoking cessation and reducing smoking prevalence
Tattan-Birch, H, Hartmann-Boyce, J, Kock, L, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Tobacco AddictionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
13
No studies
2
Included studies
NR
No studies 2 · 13.3%Ungraded 0 · 0%Very low 8 · 53.3%Low 2 · 13.3%Moderate 3 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Heated tobacco use compared with cigarette smoking
Population: people who smoke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adverse events – measured by self‐report Heated tobacco use vs cigarette smoking | RR 1.03 [0.92, 1.15] | 6 studies · 1713 participants | Low Downgraded: risk of bias, imprecision |
Serious adverse events – measured by self‐report and medical records Heated tobacco use vs cigarette smoking | RR 0.79 [0.33, 1.94] | 9 studies · 2009 participants | Very low Downgraded: risk of bias, imprecision |
NNALat Heated tobacco use vs cigarette smoking | 0.81 | 10 studies · 1959 participants | Moderate Downgraded: risk of bias |
COHbat Heated tobacco use vs cigarette smoking | 0.74 | 9 studies · 1807 participants | Moderate Downgraded: risk of bias |
Heated tobacco use compared with abstinence from tobacco
Population: people who smoke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Smoking cessation – not measured Heated tobacco use vs abstinence from tobacco | no estimate extracted | NR | No studies |
Adverse events – measured by self‐report Heated tobacco use vs abstinence from tobacco | RR 1.12 [0.86, 1.46] | 2 studies · 237 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events – measured by self‐report and medical records Heated tobacco use vs abstinence from tobacco | no estimate extracted | 5 studies · 533 participants | Very low Downgraded: risk of bias, imprecision |
NNALat Heated tobacco use vs abstinence from tobacco | 0.5 | 5 studies · 382 participants | Moderate Downgraded: risk of bias |
COHb at Heated tobacco use vs abstinence from tobacco | 0.69 | 3 studies · 212 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Heated tobacco use compared with snus use
Population: people who smoke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Smoking cessation – not measured Heated tobacco use vs snus use | no estimate extracted | NR | No studies |
Adverse events – measured by self‐report Heated tobacco use vs snus use | RR 1.3 [0.94, 1.8] | 1 study · 87 participants | Very low Downgraded: imprecision, indirectness |
Serious adverse events – measured by self‐report and medical records Heated tobacco use vs snus use | no estimate extracted | 1 study · 44 participants | Very low Downgraded: imprecision, indirectness |
NNAL at Heated tobacco use vs snus use | MD 160 | 1 study · 50 participants | Very low Downgraded: imprecision, indirectness |
COHb at Heated tobacco use vs snus use | MD 2.24 | 1 study · 52 participants | Low Downgraded: indirectness |
Population‐level impact of heated tobacco on cigarette smoking prevalence
Population: ‐level impact of heated tobacco on cigarette smoking prevalence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cigarette sales – | no estimate extracted | 2 studies · 2 participants | Very low Downgraded: risk of bias, imprecision, indirectness |