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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

38 questions in 9 reviews · HIV/AIDS

current versions
No studies 38 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Doctor vs community health worker
Outcomes2 · HIV infected patients on antiretroviral therapy.
Task shifting from doctors to non‐doctors for initiation and maintenance of antiretroviral therapy (2014) · Cochrane
no estimate extractedNRNo studies
Hepatitis B vaccination vs placebo
Hepatitis B Virus infection ‐ not measured · Persons with HIV infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection (2014) · Cochrane
no estimate extractedNRNo studies
Hepatitis B vaccination vs placebo
Hepatitis B virus morbidity ‐ not measured · Persons with HIV infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection (2014) · Cochrane
no estimate extractedNRNo studies
Hepatitis B vaccination vs placebo
Hepatitis B virus related mortality ‐ not measured · Persons with HIV infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection (2014) · Cochrane
no estimate extractedNRNo studies
Hepatitis B vaccination vs placebo
All cause mortality ‐ not measured · Persons with HIV infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection (2014) · Cochrane
no estimate extractedNRNo studies
IMMEDIATE initiation of cART vs DEFERRED initiation of cART
Patient or population: HIV‐positive, treatment‐naive children aged 24 to 59 months (2 to 5 years old)Settings: Thailand and CambodiaIntervention: IMMEDIATE initiation of cARTComparison: DEFERRED initiation of cART · HIV‐positive, treatment‐naive children aged one to 12 years old
Optimal time for initiating antiretroviral therapy (ART) in HIV‐infected, treatment‐naive children aged 2 to… (2013) · Cochrane
no estimate extractedNRNo studies
HAART regimen + topical treatment vs HAART regimen alone
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo
Pain relief · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical thalidomide vs Another topical agent or placebo
Pain relief · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical corticosteroids vs Another topical agent or placebo
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
HAART regimen + topical treatment vs HAART regimen alone
Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical thalidomide vs Another topical agent or placebo
Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical corticosteroids vs Another topical agent or placebo
Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo
Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical corticosteroids vs Another topical agent or placebo
Pain relief · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo
Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical corticosteroids vs Another topical agent or placebo
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical corticosteroids vs Another topical agent or placebo
Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
HAART regimen + topical treatment vs HAART regimen alone
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Intervention NR
CD4+ count · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.
Effectiveness and safety of first-line tenofovir + emtricitabine + efavirenz for patients with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Adherence ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Mortality ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Quality of life ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Topical thalidomide vs Another topical agent or placebo
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
HAART regimen + topical treatment vs HAART regimen alone
Pain relief · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
HAART regimen + topical treatment vs HAART regimen alone
Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Antiseptic mouthwash (e.g. chlorhexidine) vs Another topical agent or placebo
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical thalidomide vs Another topical agent or placebo
Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Topical thalidomide vs Another topical agent or placebo
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
Topical treatments for HIV‐related oral ulcers (2012) · Cochrane
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…0 studiesNo studies
Intervention NR
Incidence of STI3 ‐ not reported · patients with women living with HIV
Behavioral interventions to promote condom use among women living with HIV (2011) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mortality ‐ not measured · patients with first‐line ART failure
Antiretroviral regimens for patients with HIV who fail first‐line antiretroviral therapy (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Disease progression ‐ not measured · patients with first‐line ART failure
Antiretroviral regimens for patients with HIV who fail first‐line antiretroviral therapy (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adherence/tolerability/retention ‐ not reported · patients with first‐line ART failure
Antiretroviral regimens for patients with HIV who fail first‐line antiretroviral therapy (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severity diarrhoea ‐ not reported · patients with HIV exposure (children)
Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe adverse events ‐ not reported · patients with HIV infection or exposure
Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Anthropometric outcomes ‐ not reported · patients with HIV infection or exposure
Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mortality, diarrhoea‐specific ‐ not reported · patients with HIV exposure (children)
Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection (2010) · Cochrane
no estimate extractedNRNo studies