Cochrane · systematic review · CD007331
Task shifting from doctors to non‐doctors for initiation and maintenance of antiretroviral therapy
Kredo, T, Adeniyi, FB, Bateganya, M, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
15
No studies
1
Included studies
NR
No studies 1 · 6.3%Ungraded 0 · 0%Very low 5 · 31.3%Low 1 · 6.3%Moderate 7 · 43.8%High 2 · 12.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Doctor versus nurse or clinical officer for initiation and maintenance of antiretroviral therapy for HIV‐infected patients
Population: HIV‐infected patients
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (RCTs) Doctor vs nurse or clinical officer | RR 0.96 [0.82, 1.12] | 1 study · 2770 participants | High |
Death (Cohorts) Doctor vs nurse or clinical officer | RR 1.23 [1.14, 1.33] | 2 studies · 39160 participants | Low Downgraded: risk of bias |
Lost to Doctor vs nurse or clinical officer | RR 0.73 [0.55, 0.97] | 1 study · 2770 participants | Moderate Downgraded: imprecision |
Lost to Doctor vs nurse or clinical officer | RR 0.3 [0.05, 1.94] | 2 studies · 39156 participants | Very low Downgraded: imprecision |
Death or loss to Doctor vs nurse or clinical officer | RR 0.89 [0.79, 1.01] | 1 study · 2770 participants | High |
Death or loss to Doctor vs nurse or clinical officer | RR 0.72 [0.48, 1.07] | 2 studies · 39160 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Doctor versus nurse or clinical officer for maintenance of antiretroviral therapy for HIV infected patients on antiretroviral therapy
Population: HIV infected patients on antiretroviral therapy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (RCTs) Doctor vs nurse or clinical officer | RR 0.89 [0.59, 1.32] | 2 studies · 4332 participants | Moderate Downgraded: imprecision |
Death (Cohorts) Doctor vs nurse or clinical officer | RR 0.19 [0.05, 0.78] | 1 study · 2772 participants | Very low Downgraded: imprecision |
Lost to Doctor vs nurse or clinical officer | RR 1.27 [0.92, 1.77] | 2 studies · 4332 participants | Moderate Downgraded: imprecision |
Lost to Doctor vs nurse or clinical officer | RR 0.34 [0.18, 0.66] | 1 study · 2772 participants | Very low Downgraded: imprecision |
Death or loss to Doctor vs nurse or clinical officer | RR 1.1 [0.86, 1.41] | 2 studies · 4332 participants | Moderate Downgraded: imprecision |
Death or loss to Doctor vs nurse or clinical officer | RR 0.3 [0.17, 0.54] | 1 study · 2772 participants | Very low Downgraded: imprecision |
Doctor versus community health worker for maintenance of antiretroviral therapy for HIV infected patients on antiretroviral therapy.
Population: HIV infected patients on antiretroviral therapy.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes2 Doctor vs community health worker | no estimate extracted | NR | No studies |
Death (RCTs) Doctor vs community health worker | RR 1 [0.62, 1.62] | 1 study · 559 participants | Moderate Downgraded: imprecision |
Lost to Doctor vs community health worker | RR 0.52 [0.12, 2.3] | 1 study · 559 participants | Moderate Downgraded: imprecision |
Death or lost to Doctor vs community health worker | RR 0.93 [0.6, 1.46] | 1 study · 559 participants | Moderate Downgraded: imprecision |