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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

272 questions in 49 reviews · Heart

current versions
No studies 272 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Mindfulness‐based interventions (MBIs) vs active comparators
Clinical CVD events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs active comparators
Well‐being · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs active comparators
Adverse events · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs active comparators
Smoking cessation · people at high risk of or with cardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Clinical CVD events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Perceived stress · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Well‐being · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Adverse events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Transcendental meditation (TM) vs non‐active comparators
Smoking cessation · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Mindfulness‐based interventions (MBIs) vs active comparators
Adverse events · people at high risk of or withcardiovascular disease
Meditation for the primary and secondary prevention of cardiovascular disease (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Cardiovascular mortality ‐ not measured · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
no estimate extractedNRNo studies
Class I and/or III antiarrhythmics vs control
Outcomes at > 3 to 6 months after ablation · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I antiarrhythmics vs control
Adverse events: thromboembolic events · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I antiarrhythmics vs control
Adverse events: myocardial infarction · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I antiarrhythmics vs control
Adverse events: new diagnosis of heart failure · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I antiarrhythmics vs control
All‐cause mortality · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class III antiarrhythmics vs control
Outcomes at > 3 to 6 months after ablation · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class III antiarrhythmics vs control
Adverse events: myocardial infarction · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class III antiarrhythmics vs control
Adverse events: new diagnosis of heart failure · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I and/or III antiarrhythmics vs control
Adverse events: new diagnosis of heart failure · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Class I antiarrhythmics vs control
Outcomes at > 3 to 6 months after ablation · Human trial participants undergoing ablation for atrial fibrillation
Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause hospital admission (number of events) ‐ not reported
Social network interventions to support cardiac rehabilitation and secondary prevention in the management of… (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events ‐ not reported
Social network interventions to support cardiac rehabilitation and secondary prevention in the management of… (2023) · Cochrane
no estimate extractedNRNo studies
Effects of high‐ vs low‐added sugar consumption
Cardiovascular event · Adults without diabetes or CVD
High versus low‐added sugar consumption for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Effects of high‐ vs low‐added sugar consumption
All‐cause mortality · Adults without diabetes or CVD
High versus low‐added sugar consumption for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Constipation at 3 to < 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase only)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Constipation at 3 to < 12 months ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase only)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Change in body weight (kg) at 3 to < 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
PCC vs FVIIa
Adverse events · cardiac surgery for the treatment of non‐surgical bleeding
Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding (2022) · Cochrane
no estimate extractedNRNo studies
PCC vs standard treatment
Adverse events · cardiac surgery for the treatment of non‐surgical bleeding
Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcomes ( · health professionals from the USA and participants (“healthy volunteers from the Biobank cohort”) from the UK
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause mortality · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐fatal MI · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Stroke · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Peripheral artery disease · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Type 2 diabetes · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Stroke · health professionals from the USA and participants (“healthy volunteers from the Biobank cohort”) from the UK
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Peripheral artery disease · health professionals from the USA and participants (“healthy volunteers from the Biobank cohort”) from the UK
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Systolic blood pressure · health professionals from the USA and participants (“healthy volunteers from the Biobank cohort”) from the UK
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cardiovascular mortality · healthy normal weighted participants recruited through leaflets from Italy
Effects of a gluten‐reduced or gluten‐free diet for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Warfarin vs placebo or no treatment
Stroke · people with heart failure in sinus rhythm
Anticoagulation versus placebo for heart failure in sinus rhythm (2021) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs placebo or no intervention
Quality of life at 24±6 months · patients with coronary heart disease
Antibiotics for secondary prevention of coronary heart disease (2021) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs placebo or no intervention
Serious adverse event at maximum · patients with coronary heart disease
Antibiotics for secondary prevention of coronary heart disease (2021) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs placebo or no intervention
Quality of life at maximum · patients with coronary heart disease
Antibiotics for secondary prevention of coronary heart disease (2021) · Cochrane
no estimate extractedNRNo studies