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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Exercise vs ACBT
Adherence · adolescents and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs ACBT
Need for extra antibiotics (days) · adolescents and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise plus PD&P vs PD&P only
Change in VO2 peak during maximal exercise · children and young adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Effects of high‐ vs low‐added sugar consumption
Cardiovascular event · Adults without diabetes or CVD
High versus low‐added sugar consumption for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Effects of high‐ vs low‐added sugar consumption
All‐cause mortality · Adults without diabetes or CVD
High versus low‐added sugar consumption for the primary prevention of cardiovascular disease (2022) · Cochrane
no estimate extractedNRNo studies
Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)
Time to mature · CKD patients who underwent AVF creation
Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access (2022) · Cochrane
no estimate extractedNRNo studies
Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)
Dialysis efficacy indicator · CKD patients who underwent AVF creation
Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access (2022) · Cochrane
no estimate extractedNRNo studies
Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)
Vascular access function · CKD patients who underwent AVF creation
Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access (2022) · Cochrane
no estimate extractedNRNo studies
Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)
Adverse events · CKD patients who underwent AVF creation
Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Constipation at 3 to < 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase only)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Weight loss of at least 5% at ≥ 12 months ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Constipation at 3 to < 12 months ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase only)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets
Change in body weight (kg) at 3 to < 12 months ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)
Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Specimen · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index…
Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Specimen · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index…
Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children (2022) · Cochrane
no estimate extractedNRNo studies
Motion control vs neutral / cushioned running shoes
Runner satisfaction with footwear · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Motion control vs neutral / cushioned running shoes
Adverse events (e.g. skin complaints) other than musculoskeletal injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Motion control vs neutral / cushioned running shoes
Number of runners requiring hospital admission or surgery, or both, for musculoskeletal injury or adverse event · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Soft vs hard running shoes
Number of lower‐limb running injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Soft vs hard running shoes
Number of runners who failed to return to running or their previous level of running · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Soft vs hard running shoes
Runner satisfaction with footwear · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Soft vs hard running shoes
Adverse events (e.g. skin complaints) other than musculoskeletal injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Soft vs hard running shoes
Number of runners requiring hospital admission or surgery, or both, for musculoskeletal injury or adverse event · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Neutral / cushioned vs minimalist running shoes
Number of lower‐limb running injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture
Number of runners sustaining a lower‐limb running injury · military personnel
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture
Number of runners who failed to return to running or their previous level of running · military personnel
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture
Runner satisfaction with footwear · military personnel
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture
Adverse events (e.g. skin complaints) other than musculoskeletal injuries · military personnel
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Running shoes recommended and selected on foot posture vs running shoes not recommended and selected on foot posture
Number of runners requiring hospital admission or surgery, or both, for musculoskeletal injury or adverse event · military personnel
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Neutral / cushioned vs minimalist running shoes
Number of runners who failed to return to running or their previous level of running · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Neutral / cushioned vs minimalist running shoes
Adverse events (e.g. skin complaints) other than musculoskeletal injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Neutral / cushioned vs minimalist running shoes
Number of runners requiring hospital admission or surgery, or both, for musculoskeletal injury or adverse event · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Motion control vs neutral / cushioned running shoes
Number of lower‐limb running injuries · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
Motion control vs neutral / cushioned running shoes
Number of runners who failed to return to running or their previous level of running · healthy adults participating in recreational running
Running shoes for preventing lower limb running injuries in adults (2022) · Cochrane
no estimate extractedNRNo studies
LHC + Dor vs LHC + angle of His accentuation
Postoperative pathological acid reflux · adult patients (> 18 years) with achalasia
Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Test · adults with glioma Role: 1p/19q status is used for diagnosis, to inform treatment decisions and to give information on…
Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Test · adults with glioma Role: 1p/19q status is used for diagnosis, to inform treatment decisions and to give information on…
Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in… (2022) · Cochrane
no estimate extractedNRNo studies
Berotralstat vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
C1 esterase inhibitor vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
C1 esterase inhibitor vs placebo or active control
Disability (any validated scale) (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Plasma‐derived C1 esterase inhibitor vs placebo or active control
Risk of HAE attacks (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Plasma‐derived C1 esterase inhibitor vs placebo or active control
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Plasma‐derived C1 esterase inhibitor vs placebo or active control
Disability(any validated scale) (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Nanofiltered C1 esterase inhibitor vs placebo or active control
Risk of HAE attacks (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies
Avoralstat vs placebo
Mortality (during · children or adults with Types I or II HAE
Interventions for the long‐term prevention of hereditary angioedema attacks (2022) · Cochrane
no estimate extractedNRNo studies