Cochrane · systematic review · CD013285
Exercise versus airway clearance techniques for people with cystic fibrosis
Heinz, KD, Walsh, A, Southern, KW, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
8
No studies
13
Included studies
NR
No studies 13 · 61.9%Ungraded 0 · 0%Very low 8 · 38.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Exercise compared with ACBT for people with cystic fibrosis
Population: adolescents and adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pulmonary function: absolute change FEV1 % predicted Exercise vs ACBT | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Change in VO2 peak during maximal exercise Exercise vs ACBT | no estimate extracted | NR | No studies |
Quality of life Exercise vs ACBT | no estimate extracted | NR | No studies |
Adverse effects Exercise vs ACBT | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |
Participant preference: VAS score for treatment effectiveness and preference. Exercise vs ACBT | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |
Adherence Exercise vs ACBT | no estimate extracted | NR | No studies |
Need for extra antibiotics (days) Exercise vs ACBT | no estimate extracted | NR | No studies |
Exercise plus PD&P compared with PD&P only for people with cystic fibrosis
Population: children and young adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pulmonary function: absolute change FEV1 % predicted Exercise plus PD&P vs PD&P only | no estimate extracted | 2 studies · 55 participants | Very low Downgraded: risk of bias, imprecision |
Change in VO2 peak during maximal exercise Exercise plus PD&P vs PD&P only | no estimate extracted | NR | No studies |
Quality of Life: change in CFQ‐R score Exercise plus PD&P vs PD&P only | no estimate extracted | NR | No studies |
Adverse effects Exercise plus PD&P vs PD&P only | no estimate extracted | 1 study · 17 participants | Very low Downgraded: risk of bias, imprecision |
Participant preference Exercise plus PD&P vs PD&P only | no estimate extracted | NR | No studies |
Adherence Exercise plus PD&P vs PD&P only | no estimate extracted | 1 study · 17 participants | Very low Downgraded: risk of bias, imprecision |
Need for extra antibiotics (days) Exercise plus PD&P vs PD&P only | no estimate extracted | NR | No studies |
Exercise compared with underwater PEP (uPEP; also known as bubble PEP) for people with cystic fibrosis
Population: children and adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pulmonary function: absolute change FEV1 % predicted Exercise vs underwater PEP (uPEP; also known | no estimate extracted | NR | No studies |
Change in VO2 peak during maximal exercise Exercise vs underwater PEP (uPEP; also known | no estimate extracted | NR | No studies |
Quality of life: change in CFQ‐R score Exercise vs underwater PEP (uPEP; also known | no estimate extracted | NR | No studies |
Adverse effects Exercise vs underwater PEP (uPEP; also known | no estimate extracted | 1 study · 13 participants | Very low Downgraded: risk of bias, imprecision |
Participant preference: VAS test and a questionnaire to evaluate acceptability of technique to participants Exercise vs underwater PEP (uPEP; also known | no estimate extracted | 1 study · 13 participants | Very low Downgraded: risk of bias, imprecision |
Adherence Exercise vs underwater PEP (uPEP; also known | no estimate extracted | NR | No studies |
Need for extra antibiotics (days) Exercise vs underwater PEP (uPEP; also known | no estimate extracted | NR | No studies |