Cochrane · systematic review · CD013386

Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia

Midya, S, Ghosh, D, Mahmalat, MW · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 0 · 0%Very low 1 · 12.5%Low 4 · 50%Moderate 1 · 12.5%High 1 · 12.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

LHC + Dor compared to LHC without fundoplication for achalasia

Population: adult patients (> 18 years) with achalasia
2 questions
OutcomeEffectEvidenceStatus / GRADE
Postoperative pathological acid reflux
LHC + Dor vs LHC without fundoplication
RR 0.37 [0.07, 1.89]2 studies · 97 participantsVery low
Downgraded: inconsistency, indirectness
Severe postoperative dysphagia
LHC + Dor vs LHC without fundoplication
RR 3 [0.34, 26.33]3 studies · 143 participantsLow
Downgraded: imprecision, indirectness

LHC + Dor compared to LHC + Toupet for achalasia

Population: adult patients (> 18 years) with achalasia
2 questions
OutcomeEffectEvidenceStatus / GRADE
Postoperative pathological acid reflux
LHC + Dor vs LHC + Toupet
RR 0.75 [0.23, 2.43]3 studies · 105 participantsLow
Downgraded: imprecision, inconsistency
Severe postoperative dysphagia
LHC + Dor vs LHC + Toupet
RR 0.78 [0.19, 3.15]3 studies · 123 participantsLow
Downgraded: imprecision, indirectness

LHC + Dor compared to LHC + Nissen for achalasia

Population: adult patients (> 18 years) with achalasia
2 questions
OutcomeEffectEvidenceStatus / GRADE
Postoperative pathological acid reflux
LHC + Dor vs LHC + Nissen
RR 4.72 [0.23, 96.59]1 study · 138 participantsLow
Downgraded: imprecision
Severe postoperative dysphagia
LHC + Dor vs LHC + Nissen
RR 0.19 [0.04, 0.83]1 study · 138 participantsHigh

LHC + Dor compared to LHC + angle of His accentuation for achalasia

Population: adult patients (> 18 years) with achalasia
2 questions
OutcomeEffectEvidenceStatus / GRADE
Postoperative pathological acid reflux
LHC + Dor vs LHC + angle of His accentuation
no estimate extractedNRNo studies
Severe postoperative dysphagia
LHC + Dor vs LHC + angle of His accentuation
RR 1.56 [0.27, 8.95]1 study · 110 participantsModerate
Downgraded: imprecision