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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Costs · overweight or obese adults
Green tea for weight loss and weight maintenance in overweight or obese adults (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs placebo
Pain · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs placebo
Patient global assessment · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs placebo
Health Related Quality of Life · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs placebo
Pain · patients with chronic cout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs placebo
Patient global assessment · patients with chronic cout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs placebo
Health Related Quality of Life · patients with chronic cout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs allopurinol
Pain · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs allopurinol
Patient global assessment · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs allopurinol
Health Related Quality of Life · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs placebo
Pain · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs allopurinol
Pain · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs allopurinol
Patient global assessment · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 80 mg/day vs allopurinol
Health Related Quality of Life · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs allopurinol
Pain · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs allopurinol
Patient global assessment · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs placebo
Patient global assessment · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 120 mg/day vs allopurinol
Health Related Quality of Life · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Febuxostat 40 mg/day vs placebo
Health Related Quality of Life · patients with chronic gout
Febuxostat for treating chronic gout (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically apparent hepatitis A ( · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically apparent hepatitis A ( · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Hepatitis A‐related mortality · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Lack of sero‐protection, (anti HAV IgG < 10mIU/L) (low risk of bias) Maiwald 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Lack of sero‐protection, (anti HAV IgG < 10mIU/L) (all included trials) Maiwald 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐serious local adverse events (low risk of bias) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐serious local adverse events (all included studies) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐serious systemic adverse events (low risk of bias) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Non‐serious systemic adverse events (all included studies) live attenuated HAV vaccine ICH‐GCP 1997 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically apparent hepatitis A (live attenuated HAV vaccines) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically apparent hepatitis A (Dose of live attenuated HAV vaccine, titre >= TCID50 ) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically apparent hepatitis A (Dose of live attenuated HAV vaccine, titre < TCID50 ) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.
Hepatitis A immunisation in persons not previously exposed to hepatitis A (2012) · Cochrane
no estimate extractedNRNo studies
Amitriptyline vs placebo
Death due to suicide · adults with major depressive disorder
Amitriptyline versus placebo for major depressive disorder (2012) · Cochrane
no estimate extractedNRNo studies
Amitriptyline vs placebo
Quality of life · adults with major depressive disorder
Amitriptyline versus placebo for major depressive disorder (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion below 30/100 mm on VAS · painful diabetic neuropathy
Lacosamide for neuropathic pain and fibromyalgia in adults (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of life measure · painful diabetic neuropathy
Lacosamide for neuropathic pain and fibromyalgia in adults (2012) · Cochrane
no estimate extractedNRNo studies
Cytarabine plus high‐dose methotrexate vs high‐dose methotrexate alone
Serious adverse events · patients with primary CNS lymphoma
Role of chemotherapy additional to high‐dose methotrexate for primary central nervous system lymphoma (PCNSL) (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Morbidity · patients with type 2 diabetes mellitus
Colesevelam for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mortality · patients with type 2 diabetes mellitus
Colesevelam for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · patients with type 2 diabetes mellitus
Colesevelam for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Functional outcomes · patients with type 2 diabetes mellitus
Colesevelam for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Costs · patients with type 2 diabetes mellitus
Colesevelam for type 2 diabetes mellitus (2012) · Cochrane
no estimate extractedNRNo studies
Ergonomic keyboard vs placebo
Short‐term overall improvement ‐ not measured · people with carpal tunnel syndrome
Ergonomic positioning or equipment for treating carpal tunnel syndrome (2012) · Cochrane
no estimate extractedNRNo studies
Ergonomic keyboard vs placebo
Adverse effects ‐ not measured · people with carpal tunnel syndrome
Ergonomic positioning or equipment for treating carpal tunnel syndrome (2012) · Cochrane
no estimate extractedNRNo studies
Ergonomic keyboard vs placebo
Long‐term improvement in functional ability (> 3 months) ‐ not measured · people with carpal tunnel syndrome
Ergonomic positioning or equipment for treating carpal tunnel syndrome (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Adherence ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Mortality ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
Motivational interviewing vs control
Quality of life ‐ not measured · patients with Improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV (2012) · Cochrane
no estimate extractedNRNo studies
MAOIs vs placebo
Physical function · patients with fibromyalgia syndrome
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome (2012) · Cochrane
no estimate extractedNRNo studies
MAOIs vs placebo
Sleep disturbance · patients with fibromyalgia syndrome
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome (2012) · Cochrane
no estimate extractedNRNo studies
Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline
Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane
no estimate extracted0 studiesNo studies