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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Short‐term mortality · people with necrotising pancreatitis
Interventions for necrotising pancreatitis (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Organ failure · people with necrotising pancreatitis
Interventions for necrotising pancreatitis (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events (number) · people with necrotising pancreatitis
Interventions for necrotising pancreatitis (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Short‐term mortality · patients with pancreatic pseudocysts
Management strategies for pancreatic pseudocysts (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Hospital stay · patients with pancreatic pseudocysts
Management strategies for pancreatic pseudocysts (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Costs · patients with pancreatic pseudocysts
Management strategies for pancreatic pseudocysts (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Serious adverse events · patients with pancreatic pseudocysts
Management strategies for pancreatic pseudocysts (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · patients with pancreatic pseudocysts
Management strategies for pancreatic pseudocysts (2016) · Cochrane
no estimate extractedNRNo studies
Very early cerebral revascularization vs delayed treatment
Lenght of hospital stay · people with recently symptomatic carotid artery stenosis
Immediate versus delayed treatment for recently symptomatic carotid artery stenosis (2016) · Cochrane
no estimate extractedNRNo studies
Very early cerebral revascularization vs delayed treatment
Myocardial infarction < 30 days · people with recently symptomatic carotid artery stenosis
Immediate versus delayed treatment for recently symptomatic carotid artery stenosis (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Participants with at least one adverse event · adults with acute postoperative pain
Single dose dipyrone (metamizole) for acute postoperative pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs antiseptic
Wounds healed 5‐14 days · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs no topical antibiotic.
Anaphylaxis · people presenting for surgery where healing of surgical wound(s) was planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs no topical antibiotic.
Patterns of antibiotic resistance · people presenting for surgery where healing of surgical wound(s) was planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs no topical antibiotic.
Wounds healed 5‐14 days · people presenting for surgery where healing of surgical wound(s) was planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs antiseptic
Anaphylaxis · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs antiseptic
Patterns of antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics for preventing surgical site infection in wounds healing by primary intention (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cumulative pain score from the end of operation (0 hours) to 72 hours · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Time to first postoperative opioid dose · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Percentage of participants not requiring postoperative opioids over initial 72 hours · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health economic assessment · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Incidence of adverse events within 30 days of surgery · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Patient‐reported outcomes · adults aged ≥ 18 years undergoing elective surgery at any surgical site
Liposomal bupivacaine peripheral nerve block for the management of postoperative pain (2016) · Cochrane
no estimate extractedNRNo studies
Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy
Serious adverse events · people requiring surgery for chronic pancreatitis
Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis (2016) · Cochrane
no estimate extractedNRNo studies
Therapist‐supported ICBT vs face‐to‐face CBT
Adverse events at post‐treatment ‐ not reported · adults with anxiety disorders
Therapist‐supported Internet cognitive behavioural therapy for anxiety disorders in adults (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinical improvement in pulse rate · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia
Pharmacological interventions for clozapine‐induced sinus tachycardia (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Improvement in heart rate · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia
Pharmacological interventions for clozapine‐induced sinus tachycardia (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Duration of hospitalisation · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia
Pharmacological interventions for clozapine‐induced sinus tachycardia (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinically important adverse events · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia
Pharmacological interventions for clozapine‐induced sinus tachycardia (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Patient satisfaction · adults with schizophrenia or related disorders treated for clozapine‐induced tachycardia
Pharmacological interventions for clozapine‐induced sinus tachycardia (2016) · Cochrane
no estimate extractedNRNo studies
Hydroxyurea vs placebo or standard care
Frequency of transfusion · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Hydroxyurea vs placebo or standard care
Major adverse effects · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Hydroxyurea vs placebo or standard care
Quality of life · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Hydroxyurea vs placebo or standard care
Mean Hb F (g/dL) · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Frequency of transfusion · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of life · people with non‐transfusion dependent beta thalassaemia
Hydroxyurea for reducing blood transfusion in non‐transfusion dependent beta thalassaemias (2016) · Cochrane
no estimate extractedNRNo studies
Oral hydromorphone vs placebo
Substantial benefit: ≥ 50% reduction in pain PGIC much improved · adults with chronic neuropathic pain
Hydromorphone for neuropathic pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Oral hydromorphone vs placebo
Moderate benefit: ≥ 30% reduction in pain PGIC much or very much improved · adults with chronic neuropathic pain
Hydromorphone for neuropathic pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Oral hydromorphone vs placebo
Serious adverse events · adults with chronic neuropathic pain
Hydromorphone for neuropathic pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Oral hydromorphone vs placebo
Deaths · adults with chronic neuropathic pain
Hydromorphone for neuropathic pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Substantial benefit: at least 50% reduction in pain, or PGIC much improved · Adults with chronic neuropathic pain
Fentanyl for neuropathic pain in adults (2016) · Cochrane
no estimate extractedNRNo studies
Amnioinfusion vs no amnioinfusion
Perinatal death or severe morbidity (neonatal encephalopathy, intraventricular haemorrhage, admission to intensive/high care) · pregnant women with confirmed or suspected chorioamnionitis
Amnioinfusion for chorioamnionitis (2016) · Cochrane
no estimate extractedNRNo studies
Amnioinfusion vs no amnioinfusion
Low Apgar score at five minutes (less than seven or as defined by trial authors) · pregnant women with confirmed or suspected chorioamnionitis
Amnioinfusion for chorioamnionitis (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Number of participants with IAD (new) · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Number of participants not satisfied with treatment · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Number of participants with pain due to IAD · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Number of participants with pain due to skin care product or procedure · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Adverse reaction due to the skin care product or procedure, e.g. skin irritation, rash, itching, allergic reaction · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure
Incremental cost‐effectiveness · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies
Any method of application of a topical skin care product vs another method of application of the topical skin care product
Number of participants with IAD (residual, i.e. not healed) · adults with incontinence
Interventions for preventing and treating incontinence‐associated dermatitis in adults (2016) · Cochrane
no estimate extractedNRNo studies