Cochrane · systematic review · CD011605

Fentanyl for neuropathic pain in adults

Derry, S, Stannard, C, Cole, P, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: Adults with chronic neuropathic pain
6 questions
OutcomeEffectEvidenceStatus / GRADE
Moderate benefit: at least 30% reduction in pain, or PGIC much or very much improved
no estimate extracted1 study · 163 participantsVery low
Substantial benefit: at least 50% reduction in pain, or PGIC much improved
no estimate extractedNRNo studies
Lack of efficacy withdrawal in randomised double‐blind phase
no estimate extracted1 study · 163 participantsVery low
Adverse event withdrawal in randomised double‐blind phase
no estimate extracted1 study · 163 participantsVery low
Serious adverse events
no estimate extracted1 study · 258 participantsVery low
Deaths
no estimate extracted1 study · 258 participantsVery low