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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

249 questions in 68 reviews · Airways

current versions
No studies 249 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care
Quality of sleep
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) vs bilevel ventilation
Time to life‐saving cardiovascular intervention
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control
Central AHI
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control
Serious adverse events
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control
Quality of sleep
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control
Time to life‐saving cardiovascular intervention
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care
Quality of life
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)
Central AHI
Non‐invasive positive pressure ventilation for central sleep apnoea in adults (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen
Exacerbation frequency · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen
Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 14 days on/off placebo regimen
Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
Pulmonary rehabilitation vs usual care
Adverse events · Adults with asthma
Pulmonary rehabilitation versus usual care for adults with asthma (2022) · Cochrane
no estimate extractedNRNo studies
Nebulised magnesium sulfate + standard care vs placebo + standard care
Proportion of people with serious adverse events · acute exacerbations of chronic obstructive pulmonary disease
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane
no estimate extractedNRNo studies
Magnesium sulfate vs standard care (ipratropium bromide)
Proportion of people with serious adverse events · acute exacerbations of chronic obstructive pulmonary disease
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane
no estimate extractedNRNo studies
Magnesium sulfate vs standard care (ipratropium bromide)
Change in oxygen saturation (SaO2) · acute exacerbations of chronic obstructive pulmonary disease
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane
no estimate extractedNRNo studies
Magnesium sulfate vs standard care (ipratropium bromide)
Change in dyspnoea score · acute exacerbations of chronic obstructive pulmonary disease
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane
no estimate extractedNRNo studies
Magnesium sulfate vs standard care (ipratropium bromide)
Lung function: FEV1 at 60 min · acute exacerbations of chronic obstructive pulmonary disease
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcome№ of participants(studies)
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescent sand adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
HD Triple vs. MD Triple · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD Triple · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcome№ of participants(studies)
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcome№ of participants(studies)
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcome№ of participants(studies)
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
MD‐ICS/LABA · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator…
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Outcome№ of participants(studies)
Effectiveness and tolerability of dual and triple combination inhaler therapies compared with each other and… (2022) · Cochrane
no estimate extractedNRNo studies
Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo
Healthcare utilisation ‐ not measured · treatment for asthma in adults and children with asthma and GORD
Pharmacological and surgical interventions for the treatment of gastro‐oesophageal reflux in adults and… (2021) · Cochrane
no estimate extractedNRNo studies
Macrolides vs placebo
Outcomesa · adults and children with chronic asthma
Macrolides versus placebo for chronic asthma (2021) · Cochrane
no estimate extractedNRNo studies
Anti‐IL13 or anti‐IL4 agents vs placebo
Time off work or study · children and adults with asthma
Anti‐interleukin‐13 and anti‐interleukin‐4 agents versus placebo, anti‐interleukin‐5 or… (2021) · Cochrane
no estimate extractedNRNo studies
Telerehabilitation vs centre‐based (outpatient) pulmonary rehabilitation
Primary rehabilitation · Chronic respiratory disease
Telerehabilitation for chronic respiratory disease (2021) · Cochrane
no estimate extractedNRNo studies
Telerehabilitation vs no rehabilitation control
Primary rehabilitation · Chronic respiratory disease
Telerehabilitation for chronic respiratory disease (2021) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) vs sham CPAP
Minor adverse events · erectile dysfunction in men with obstructive sleep apnoea
Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive… (2021) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) vs phosphodiesterase type 5 inhibitors
Health‐related quality of life · erectile dysfunction in men with obstructive sleep apnoea
Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive… (2021) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) vs no CPAP
Health‐related quality of life · erectile dysfunction in men with obstructive sleep apnoea
Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive… (2021) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) vs no CPAP
Minor adverse events · erectile dysfunction in men with obstructive sleep apnoea
Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive… (2021) · Cochrane
no estimate extractedNRNo studies
Continuous positive airway pressure (CPAP) vs sham CPAP
Serious adverse events · erectile dysfunction in men with obstructive sleep apnoea
Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
Exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
Mortality · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
Exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
Symptoms of dyspnoea · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring vs usual care
Mortality · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Exacerbations · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies