Gingival index (GI) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Persons with orofacial cleft have a higher gingival index than healthy controls (MD 0.15, 95% CI 0.11 to 0.19; low certainty).
1 finding from 1 review
Clinical attachment level (CAL) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Clinical attachment level loss is greater in persons with orofacial cleft than in healthy controls (p<0.00001), but no pooled effect size was reported (ungraded).
1 finding from 1 review
Intervention not reported
Bleeding on Probing (BoP)
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Bleeding Index (BI) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Bleeding index is significantly higher in persons with orofacial cleft than in healthy controls (p<0.0001), but no pooled effect size was reported (ungraded).
1 finding from 1 review
Oral microbiota composition · Individuals assessed for oral microbiota (mainly children and adolescents)
Oral microbiota composition differs between persons with orofacial cleft and healthy controls, synthesized qualitatively across 8 studies but not meta-analyzed (ungraded).
1 finding from 1 review
no estimate extracted
8 studies
GRADE not reported
Plaque · Patients with cleft lip and palate (CLP)
Plaque index does not differ significantly between unilateral and bilateral cleft lip and palate (MD -0.13, 95% CI -0.38 to 0.12; ungraded).
1 finding from 1 review
Probing pocket depth · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Persons with orofacial cleft have a greater probing pocket depth than healthy controls (MD 0.88, 95% CI 0.82 to 0.95; low certainty).
1 finding from 1 review
Plaque · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Persons with orofacial cleft have a higher plaque index than healthy controls (MD 0.29, 95% CI 0.24 to 0.34; low certainty).
1 finding from 1 review
Pocket closure · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
2 findings from 1 review
Three studies evaluated the proportion of closed pockets three months after treatment (Al-Zahrani 2011; Courval 2020; Rodrigues 2023); studies used different criteria to measure this outcome. All studies reported an…
3 studies
GRADE not reported
No studies measured this outcome at 6 months (SoF row labeled 'Change in pocket depth from baseline to 6 months after initial treatment').
Studies not reported
No studies found
Periodontitis (prevalence) · adults
Using adjusted ORs, caries remained associated with higher periodontitis odds (OR 1.57).
3 findings from 1 review
Dental caries prevalence · adults
With a non-standard periodontitis definition, the association persisted (OR 1.38).
12 findings from 1 review
Show 9 more findings
Patient satisfaction · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Number of ibuprofen tablets required · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
Postoperative systemic antibiotics… showed no clear difference in number of ibuprofen tablets required compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.
1 finding from 1 review
Any adverse effect related to aPDT · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
1 finding from 1 review
Risk with control: 23 studies reported that no adverse effects of aPDT were observed. Number of participants (studies): 639 (24 studies). Certainty: Moderate. (24 studies reported adverse effects, with all studies…
24 studies · 639 participants
Moderate
Quality of life · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
Pooling 3 studies, children/adolescents with CLP were about 2.03 times more likely to have dental caries than non-CLP controls (p<0.005; low heterogeneity), though most included studies were at high risk of bias; the evidence is ungraded.
1 finding from 1 review
Intervention not reported
Periodontopathogenic microbiota composition
1 finding from 1 review
Lactobacillus spp. salivary/plaque counts (cariogenic microbiota) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
A meta-analysis found no significant difference in mean Lactobacillus spp. levels between children with and without CLP, with high heterogeneity; the evidence is ungraded.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in probing pocket depth (PPD) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
Swelling (mean) · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)
The review found no eligible studies for this question.
3 findings from 1 review
No data available for this outcome.
0 studies
No studies found
RR 0.50 [0.10, 2.56]
1 study · 72 participants
Low
No data available for this outcome.
0 studies
No studies found