Question · asked by 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT: Any adverse effect related to aPDT

Population
Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Intervention
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI)
Comparison
Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Outcome
Any adverse effect related to aPDT

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT
Any adverse effect related to aPDT · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane All outcomes
Risk with control: 23 studies reported that no adverse effects of aPDT were observed. Number of participants (studies): 639 (24 studies). Certainty: Moderate. (24 studies reported adverse effects, with all studies…24 studies · 639 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases
2024 · Cochrane All outcomes
2024-02Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.