Adverse events for mother or child · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review
Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, a nano-CaF2-containing orthodontic cement showed significant enamel remineralization versus control in a single study (ungraded).
1 finding from 1 review
Dental caries in children · Children (approx. 4-18 years)
Pooling studies that used BMI as a continuous variable showed no significant association between per-unit BMI and childhood dental caries (OR 1.01, 95% CI 0.99 to 1.03; I2=3.5%); ungraded.
3 findings from 1 review
Enamel surface microhardness · Human tooth enamel specimens, sound/intact (in vitro)
In sound enamel, Er:YAG laser irradiation significantly increased surface microhardness after acid challenge versus untreated control (SMD 2.41, 95% CI 0.70 to 4.12; 3 in vitro studies; ungraded).
1 finding from 1 review
SMD 2.41 [0.70, 4.12]
3 studies
GRADE not reported
Dental caries · Children (<18 years) with vs without dental caries
ApaI(rs7975232) dominant model: CC+CA vs AA was not significantly associated with dental caries (OR 0.91); ungraded.
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
It is very uncertain whether brushed less than twice per day changes fluorosis (percentage prevalence in permanent teeth) compared with brushed twice or more per day (very low certainty).
2 findings from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.
1 study · 1398 participants
Very low
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, sex was not significantly associated with space closure (OR 1.38; not GRADE-rated).
1 finding from 1 review
Specificity · Children and adults with primary or permanent dentition undergoing dental caries assessment
Across 13 studies, the specificity of teledentistry caries diagnosis ranged from 83% to 100%; no pooled estimate and certainty not graded.
1 finding from 1 review
Mother plaque (sub- and supragingival calculus) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
Dietary advice on how to achieve a healthy diet for infants… showed no clear difference in mother plaque (sub- and supragingival calculus) compared with standard care; GRADE not reported.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Cdx-2(rs11568820) was reported by only one study and was not meta-analyzed; its association with caries risk is uncertain (ungraded).
1 finding from 1 review
Intervention not reported
Dental caries in children
The intervention led to higher dental caries in children; GRADE not reported.
1 finding from 1 review
OR 1.20 [1.04, 1.36]
4 studies
GRADE not reported
Caries arrest · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with restoration (restorative treatment) (very low certainty).
1 finding from 1 review
Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to caries experience (dmft) in the primary dentition of Brazilian children (very low certainty).
1 finding from 1 review
Caries arrestment at the individual (patient) level · Children and adults without systemic diseases affecting dental health
SDF showed a higher caries-arrestment proportion at the individual level, but the reported difference was not statistically significant.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) dominant model: TT+TG vs GG was not significantly associated with dental caries (OR 1.09); ungraded.
1 finding from 1 review
Intervention not reported
Change in Lactobacillus spp. in dental plaque
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
High salivary P. gingivalis (over 10^4 CFU/ml) · adults
Periodontitis was associated with higher odds of detectable high-level salivary P. gingivalis (OR 3.38).
1 finding from 1 review
OR 3.38 [1.46, 7.83]
2 studies
GRADE not reported
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review