Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, mean patient age was not significantly associated with space closure odds (OR 0.59 per year; not GRADE-rated).
1 finding from 1 review
Aesthetics · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
CC+CT genotype at FokI(rs10735810) was associated with ~1.87-fold higher caries risk than TT (dominant model, OR 1.87); ungraded.
1 finding from 1 review
Early childhood caries (ECC) · Children with average age >3 years
No significant association between cesarean vs vaginal delivery and ECC among children with average age >3 years (OR 1.24, 95% CI 0.89-1.71).
1 finding from 1 review
OR 1.24 [0.89, 1.71]
14 studies
GRADE not reported
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
It is very uncertain whether used a pea-sized amount of fluoride toothpaste or less changes fluorosis (percentage prevalence in permanent teeth) compared with used more than a pea-sized amount (very low certainty).
1 finding from 1 review
Intervention not reported
Veillonella spp. association with caries (qualitative)
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, distal inclination of the second molar vs upright was not significantly associated with space closure (OR 1.18; not GRADE-rated).
1 finding from 1 review
Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)
Serum 25(OH)D <50 nmol/l (vs ≥75 nmol/l) was associated with higher odds of ECC (OR 2.00; ungraded).
1 finding from 1 review
Caries experience (mean DMFT) · Adult residents of slums and non-slum urban settings of LMICs
Mean DMFT ranges from 0.26 to 16.6 across LMIC urban/slum populations; ungraded.
1 finding from 1 review
Dental trauma prevalence · Adult residents of slums and non-slum urban settings of LMICs
Dental trauma appears more common in urban and disadvantaged settings; ungraded, few studies.
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
The intervention led to lower dental caries (early childhood caries); GRADE not reported.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
OR 1.76 [0.74, 4.20]
1 study · 242 participants
Very low
No studies reported data in this dentition type
0 studies
No studies found
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) recessive model: AA vs AG+GG was not significantly associated with dental caries (OR 1.09); ungraded.
1 finding from 1 review
Negative predictive value for dental caries diagnosis · Children and adults with primary or permanent dentition
Negative predictive values were reported in 10 of the 13 studies that reported sensitivity and specificity; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
no estimate extracted
10 studies
GRADE not reported
Alveolar bone loss · Adults in case-control studies (oral cancer patients vs healthy controls)
Alveolar bone loss did not differ significantly between oral cancer patients and controls (SMD 0.18, 95% CI -2.34 to 2.69; extreme heterogeneity); ungraded.
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by WHO 2007 Z-score)
Overweight/obesity may make little or no difference to the odds of caries in the permanent dentition (low certainty).
1 finding from 1 review
OR 0.93 [0.78, 1.12]
2 studies
Low
Dental caries: prevalence of root caries · adults
Periodontitis was associated with higher root caries odds (OR 2.10).
1 finding from 1 review
Use of toothbrush and toothpaste for mouth cleaning · Adult residents of slums and non-slum urban settings of LMICs
Toothbrush/paste is the commonest cleaning method but is used less in slum/disadvantaged/rural groups than urban/non-slum groups; ungraded.
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
1 finding from 1 review
AOR 6.5
1 study
GRADE not reported
Mother microbiological presence (mutans streptococci colonisation level, CFU/mL) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
Consumption of xylitol chewing gum by women (mothers) led to higher mother microbiological presence (mutans streptococci colonisation… compared with consumption of CHX/xylitol gum by women, or CHX varnish applied to…; GRADE not reported.
1 finding from 1 review