Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Tempophore showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA); GRADE not reported.
1 finding from 1 review
Dental caries · Adult participants in 25 meta-regression studies
The Model 1 adjusted meta-regression coefficient for lower university education was -4.132903.
2 findings from 1 review
Intervention not reported
Dental caries in primary dentition (presence)
The intervention led to higher dental caries in primary dentition (presence); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Electrosurgery showed no clear difference in clinical failure compared with formocresol (FC); GRADE not reported.
1 finding from 1 review
Preterm birth stratified by gestational age at birth (moderate-to-late 32 to <37, very 28 to <32, extremely <28 weeks) · pregnant women
The planned subanalysis of preterm birth by gestational age at birth (moderate-to-late, very, extremely preterm) could not be performed because of the small number of cases and lack of stratified data in the original studies.
1 finding from 1 review
Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomesPregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs · By gestational age at birth
no estimate extracted
0 studies
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Vitapex (calcium hydroxide/iodoform) led to higher radiological failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.
1 finding from 1 review
Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Ferric sulphate (FS)
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, soft tissue, mobility, adjacent tissue inflammation, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
1 study · 135 participants
GRADE not reported
Sensitivity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled sensitivity of radiographic detection for all (initial and advanced) occlusal caries was 36.0% (95% CI 20 to 56) (ungraded).
3 findings from 1 review
Sensitivity 36.0 [20, 56]
9 studies
GRADE not reported
Sensitivity 38.6 [25, 54]
14 studies
GRADE not reported
Sensitivity 39.7 [25, 56]
11 studies
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Vitapex (calcium hydroxide/iodoform) may leads to higher clinical failure compared with zinc oxide and eugenol (ZOE) (low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Intervention not reported
Overall failure
1 finding from 1 review
no estimate extracted
2 studies
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Mineral trioxide aggregate (MTA) showed no clear difference in clinical failure compared with sodium hypochlorite (NaOCl); GRADE not reported.
1 finding from 1 review
Development and eruption of the third molar · Children aged 5 to 15 years with a compromised first permanent molar
Development and eruption of the third molar appeared accelerated after early first permanent molar extraction in two studies (e.g., eruption OR 2.86, 95% CI 1.37 to 5.96); ungraded.
1 finding from 1 review
OR 2.86 [1.37, 5.96]
2 studies
GRADE not reported
Formocresol (FC) pulpotomy vs Calcium hydroxide pulpectomy
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
The review found no eligible studies for this question.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Electrosurgery showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether ferric sulphate (FS) changes clinical failure compared with ankaferd Blood Stopper (ABS) (very low certainty).
1 finding from 1 review
Caries increment in permanent teeth · Children or adolescents
The NMR reported a difference between fluoride in rinse and placebo at randomisation years 1954 to 1990; no GRADE assessment was reported.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review