DMFT/DMFS index (dental caries experience) · Children with dental caries
Oral-health promotion programs were associated with markedly lower odds of DMFT/S in children (OR 0.19, 95% CI 0.10 to 0.39; ungraded, very high heterogeneity I2=98.5%).
1 finding from 1 review
OR 0.19 [0.10, 0.39]
8 studies
GRADE not reported
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from no treatment for arrest or reversal of approximal carious lesions (RR 2.29, 95% CI 0.74 to 7.1; very low certainty).
1 finding from 1 review
Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
The review found no eligible studies for this question.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with MTA than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 AR teeth): MTA 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; the 4 abscess-remedy failures occurred at 3 months; difference statistically…
1 study · 40 participants
GRADE not reported
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
Resin infiltration may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 0.88, 95% CI 0.4 to 1.91; very low certainty).
1 finding from 1 review
Any planned outcome (sealant retention, caries, etc.) · Patients with premolars/molars requiring pit-and-fissure sealants
No eligible studies compared laser preparation with air abrasion for fissure sealant placement (evidence gap).
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Gingivitis · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
2 findings from 1 review
Adverse effects of toothpaste · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1 finding from 1 review
Intervention not reported
Mean DMFT/dmft (caries severity) · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes
The pooled mean DMFT/dmft (caries severity) was 5.7 (SD 3.6) across 5 studies; certainty not graded.
1 finding from 1 review
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1 finding from 1 review
Dental caries prevalence · Children and adolescents with type 1 diabetes assessed with DMFT
When restricted to studies using DMFT, the pooled dental caries prevalence was 62%.
1 finding from 1 review
Prevalence 0.62
Studies not reported
GRADE not reported
Side effects · Adults, 16 years and older (dentate)
Adverse events · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
No adverse events were reported in any included study (ungraded, narrative).
1 finding from 1 review
No adverse events (pulpal sensation, post-lasing thermal sensitivity, pulpitis, or other laser-induced pathology) were reported in any of the included studies.
5 studies
GRADE not reported
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel may be less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.67, 95% CI 0.45 to 0.99; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF + potassium iodide solution (applied annually) may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 0.9, 95% CI 0.22 to 3.62; very low certainty).
1 finding from 1 review
Radiographic failure · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in radiographic failure between pulpotomy and pulpectomy in the main analysis (RR 0.79, 95% CI 0.25 to 2.42), with considerable heterogeneity (I2=76%; ungraded).
2 findings from 1 review
Quantitative light-induced fluorescence (QLF), fluorescence loss · Patients (mainly children) with white spot lesions (WSL)
Compared with baseline, CPP-ACP significantly improved white spot lesions on QLF (SMD -0.43, 95% CI -0.79 to -0.07; ungraded).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel may be less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.64, 95% CI 0.44 to 0.92; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
0.2% NaF mouthrinse + supervised toothbrushing may not differ from 1.23% APF gel for arrest or reversal of occlusal carious lesions (RR 0.91, 95% CI 0.68 to 1.22; low certainty).
1 finding from 1 review