Question · asked by 1 review

1500 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste: Adverse effects of toothpaste

Population
Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
Intervention
1500 ppm F toothpaste
Comparison
Non-fluoride (0 ppm F) placebo toothpaste
Outcome
Adverse effects of toothpaste

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
1500 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start) · 24 months
Fluoride toothpastes of different concentrations for preventing dental caries (2019) · Cochrane All outcomes
Adverse effects of toothpaste: not estimable; 0 events reported (Fan 2008); 998 participants (1 RCT); low-certainty.1 study · 998 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluoride toothpastes of different concentrations for preventing dental caries
2019 · Cochrane All outcomes
2018-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.