Non-Cochrane · prevalence · PM31521152
Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis.
Wang Yan, Xing Lin, Yu Hui, et al. · BMC oral health · 2019 · PubMed · doi:10.1186/s12903-019-0903-5
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
12
current version
GRADE rated
0
No studies
0
Included studies
11
linked below
No studies 0 · 0%Ungraded 12 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Children (under 12 years) and adolescents (12-18 years) with a validated diagnosis of type 1 diabetes; dental caries diagnosed by dmft/DMFT/DFS/dfs > 0 per WHO criteria | Children and adolescents with type 1 diabetes (538 individuals across 10 studies; ages 1-18 years; sample sizes 25-87) |
| Intervention | Prevalence of dental caries (no intervention; descriptive prevalence review) | Prevalence of dental caries (pooled 67%); mean DMFT/dmft (pooled 5.7) |
| Comparison | Not applicable for prevalence review | Not applicable for prevalence review |
| Outcomes | Prevalence of dental caries (proportion with dmft/DMFT/DFS/dfs > 0); mean DMFT/dmft | Pooled caries prevalence 67% (95% CI 0.56-0.77; I2=83%); pooled mean DMFT/dmft 5.7 (SD 3.6) |
| Study designs | Cross-sectional studies or the first evaluation of longitudinal studies; children under 12 and adolescents 12-18 years; conference abstracts with relevant data included; case reports, review articles, case-control studies, letters, and studies on young adults excluded | 10 cross-sectional studies (4 Asia, 3 Europe, 2 South America, 1 North America); modified Newcastle-Ottawa Scale (max 5 points): 1 study 4 points, 6 studies 3 points, 3 studies 2 points |
| Timing | Not specified (single time-point prevalence; search inception to 28 December 2018) | Included studies published 1997-2017 |
Search date: Inception to 28 December 2018. Databases: PubMed; EMBASE; China National Knowledge Infrastructure (CNKI)
Questions and results
Comparison
Population: Children (<12 years) and adolescents (12-18 years) with type 1 diabetes
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries prevalence Metabolic control: good Caries prevalence was lowest among those with good metabolic control at 47% (95% CI 0.30 to 0.64); certainty not graded. Source: Abstract; Results 'Subgroup and influence analysis'; Fig. 4 (subgroup forest plot by metabolic control) · same question in other reviews | Prevalence 0.47 [0.30, 0.64] | 3 studies · 54 participants | Ungraded |
Dental caries prevalence Continent: Europe Caries prevalence in European studies was 57% (95% CI 0.41 to 0.72); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 3 (subgroup forest plot by geographical region) · same question in other reviews | Prevalence 0.57 [0.41, 0.72] | 3 studies · 194 participants | Ungraded |
Mean DMFT/dmft (caries severity) The pooled mean DMFT/dmft (caries severity) was 5.7 (SD 3.6) across 5 studies; certainty not graded. Source: Results 'Quantitative synthesis' · same question in other reviews | MEAN 5.7 | 5 studies | Ungraded |
Dental caries prevalence Continent: Asia Caries prevalence in Asian studies was 67% (95% CI 0.43 to 0.85); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 3 (subgroup forest plot by geographical region) · same question in other reviews | Prevalence 0.67 [0.43, 0.85] | 4 studies · 163 participants | Ungraded |
Dental caries prevalence Continent: South America Caries prevalence was highest in South American studies at 84% (95% CI 0.67 to 0.94); certainty not graded. Source: Abstract; Results 'Subgroup and influence analysis'; Fig. 3 (subgroup forest plot by geographical region) · same question in other reviews | Prevalence 0.84 [0.67, 0.94] | 2 studies · 112 participants | Ungraded |
Dental caries prevalence The pooled prevalence of dental caries among children and adolescents with type 1 diabetes was 67% (95% CI 0.56 to 0.77), with high heterogeneity (I2=83%); certainty not graded. Source: Abstract; Results 'Quantitative synthesis'; Fig. 2 (forest plot) · same question in other reviews | Prevalence 0.67 [0.56, 0.77] | 10 studies · 538 participants | Ungraded |
Dental caries prevalence Continent: North America Caries prevalence in the single North American study was 64% (95% CI 0.52 to 0.74); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 3 (subgroup forest plot by geographical region) · same question in other reviews | Prevalence 0.64 [0.52, 0.74] | 1 study · 69 participants | Ungraded |
Dental caries prevalence Mean age: >10 years Caries prevalence was lower in those with mean age >10 years at 57% (95% CI 0.45 to 0.68); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 5 (subgroup forest plot by mean age) · same question in other reviews | Prevalence 0.57 [0.45, 0.68] | 6 studies · 338 participants | Ungraded |
Dental caries prevalence Mean age: <=10 years Caries prevalence was higher in those with mean age <=10 years at 80% (95% CI 0.74 to 0.85); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 5 (subgroup forest plot by mean age) · same question in other reviews | Prevalence 0.80 [0.74, 0.85] | 4 studies · 200 participants | Ungraded |
Dental caries prevalence Metabolic control: poor (bad) Caries prevalence among those with poor metabolic control was 66% (95% CI 0.43 to 0.83); certainty not graded. Source: Results 'Subgroup and influence analysis'; Fig. 4 (subgroup forest plot by metabolic control) · same question in other reviews | Prevalence 0.66 [0.43, 0.83] | 3 studies · 170 participants | Ungraded |
Not applicable vs Not applicable
Population: Children and adolescents with type 1 diabetes assessed with DMFT
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries prevalence Sensitivity analysis: DMFT diagnostic method When restricted to studies using DMFT, the pooled dental caries prevalence was 62%. Source: Subgroup and influence analysis · same question in other reviews | Prevalence 0.62 | NR | Ungraded |
Comparison
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries prevalence Sensitivity analysis: one-study-removed (leave-one-out) | Prevalence 0.65 to 0.70 (range) | 10 studies | Ungraded |
Included primary studies 11
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Abeuova et al. 2017 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Alavi et al. 2006 The prevalence of dental caries in 5 - 18-year-old insulin-dependent diabetics of Fars Province, southern Iran. PMID:16859062 | this review only | not stated | not extracted yet | not extracted yet |
| Carneiro et al. 2015 The influence of glycemic control on the oral health of children and adolescents with diabetes mellitus type 1. PMID:26677088 | this review only | not stated | not extracted yet | not extracted yet |
| Gomez-Diaz et al. 2012 Association between carotid intima-media thickness, buccodental status, and glycemic control in pediatric type 1 diabetes. PMID:22583477 | this review only | not stated | not extracted yet | not extracted yet |
| Karjalainen et al. 1997 Relationship between caries and level of metabolic balance in children and adolescents with insulin-dependent diabetes mellitus. PMID:8955988 | this review only | not stated | not extracted yet | not extracted yet |
| Lai et al. 2017 Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. PMID:29190700 | this review only | not stated | not extracted yet | not extracted yet |
| Miranda et al. 2013 Caries e índice de higiene oral en niños con diabetes mellitus tipo 1 DOI:10.4067/s0370-41062013000500007 | this review only | not stated | not extracted yet | not extracted yet |
| Ofilada 2013 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Ofilada 2015 Oral Health Status of Children Attending a Summer Camp for Diabetes Children DOI:10.15605/jafes.030.02.07 | this review only | not stated | not extracted yet | not extracted yet |
| Ofilada et al. 2013 Commentary on Anderson: turf protection or interprofessional cooperation? PMID:12013512 | this review only | not stated | not extracted yet | not extracted yet |
| Twetman et al. 2002 Caries incidence in young type 1 diabetes mellitus patients in relation to metabolic control and caries-associated risk factors. PMID:11961327 | this review only | not stated | not extracted yet | not extracted yet |