Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,241 questions · 3,336 findings · 1,340 reviews

No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Mosaicplasty vs microfracture

QoL · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

1 finding from 1 review

Umeclidinium bromide vs placebo

Quality of life: number of participants with clinically significant improvement (≥ 4 units) in SGRQ total score · patients with chronic obstructive pulmonary disease

Umeclidinium bromide probably leads to higher quality of life: number of participants with ≥ 4 units improvement… compared with placebo (moderate certainty).

1 finding from 1 review

ZUCLOPENTHIXOL ACETATE vs placebo

Quality of life/satisfaction with care for either recipients of care or carers: significant change in quality of life/satisfaction · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

ZUCLOPENTHIXOL DECANOATE vs placebo

Quality of life/satisfaction with care for either recipients of care or carers: significant change in quality of life/satisfaction · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

General life satisfaction Quality of Life Interview section, scale of 1 to 7 · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review