Cochrane · systematic review · CD012794
Stem cell therapy for treatment of thromboangiitis obliterans (Buerger's disease)
Cacione, DG, do Carmo Novaes, F, Moreno, DH · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
2
No studies
4
Included studies
NR
No studies 4 · 66.7%Ungraded 0 · 0%Very low 2 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Stem cell therapy (any source) compared with any other modality of treatment for thromboangiitis obliterans (Buerger's disease)
Population: individuals with thromboangiitis obliterans (Buerger's disease)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rate of amputation Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | NR | No studies |
Ulcer healing (size area) Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |
Pain Measured using a validated pain score or scale, or quality of life questionnaire Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | NR | No studies |
Adverse effects Local or systemic inflammatory response, cardiovascular abnormalities, and thromboembolic complications Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | NR | No studies |
Amputation‐free survival Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | NR | No studies |
Pain‐free walking distance Stem cell therapy (any source) vs any other modality of treatment | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |