What do systematic reviews say?

Vitrectomy vs scleral buckling

It is very uncertain whether pars plana vitrectomy (PPV) changes quality of life (satisfaction with vision) at least 3 months after… compared with scleral buckling (very low certainty).

• Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments 2019 · Cochrane Headline outcomes only
  RR 6.22 [0.88, 44.09]
  1 study · 32 participants
  Very low

Intervention not reported

• Treatments for primary delusional infestation 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 participants
  GRADE not reported

Intervention not reported

• Percutaneous vertebroplasty for osteoporotic vertebral compression fracture 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 351 participants
  High

Intervention not reported

• Home‐based multidimensional survivorship programmes for breast cancer survivors 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 308 participants
  Low

Whole body vibration plus mixed exercise vs control

• Whole body vibration exercise training for fibromyalgia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 21 participants
  Very low

Electrical stimulation vs No active treatment (control)

• Electrical stimulation with non‐implanted devices for stress urinary incontinence in women 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 250 participants
  Moderate

PFMT added to electrical stimulation vs pelvic floor muscle training (PFMT)

• Electrical stimulation with non‐implanted devices for stress urinary incontinence in women 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 193 participants
  Very low

Prevention of UI after radical: electric or magnetic energy vs no treatment

• Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Very low

Intervention not reported

• Tonsillectomy or adenotonsillectomy versus non‐surgical management for obstructive sleep‐disordered breathing in… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 395 participants
  Moderate

Varenicline vs placebo

• Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

PIMOZIDE + ANY ANTIPSYCHOTIC vs ANTIPSYCHOTIC + ANTIPSYCHOTIC

The review found no eligible studies for this question.

• Pimozide for schizophrenia or related psychoses 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dental fluorosis (assessed by TFI or WHO criteria) vs Individuals without dental fluorosis

Two studies found dental fluorosis significantly associated with poorer OHRQoL; narrative, ungraded.

• Impact of oral conditions on oral health-related quality of life among Indians- a systematic review and Meta-analysis. 2023 All outcomes

  India; community-based and institutional settings across multiple states
  Dental fluorosis and QoL (continuous, OIDP/CPQ11-14): a significant difference between individuals with and without fluorosis on OHRQoL (Nagarajappa 2015, Shyam 2020). Two studies, 3000 individuals; not pooled.
  2 studies · 3000 participants
  GRADE not reported

Summary of findings ‐ nebulisers for delivering dornase alfa conventional system vs VMT

• Nebuliser systems for drug delivery in cystic fibrosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 85 participants
  Very low

Berotralstat vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 130 participants
  Moderate

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

The review found no eligible studies for this question.

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Zoledronate vs pamidronate or risedronate

• Bisphosphonates for Paget's disease of bone in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Bisphosphonates vs placebo

• Bisphosphonates for Paget's disease of bone in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Remote versus face‐to‐face check‐ups for asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 544 participants
  Moderate

Intervention not reported

• Drug interventions for the treatment of obesity in children and adolescents 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 86 participants
  Low

SMP vs attention control

• Self‐management education programmes for osteoarthritis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  165 participants
  Low