Cochrane · systematic review · CD006349

Percutaneous vertebroplasty for osteoporotic vertebral compression fracture

Buchbinder, R, Johnston, RV, Rischin, KJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Musculoskeletal3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 2 · 28.6%High 3 · 42.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 3 versions

Vertebroplasty for osteoporotic vertebral compression fracture

Population: people with osteoporotic vertebral compression fracture
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain Scale from: 0 to 10, 0 is no pain.
no estimate extracted5 studies · 535 participantsHigh
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability.
no estimate extracted4 studies · 472 participantsHigh
Disease‐specific quality of Life (QUALEFFO) Scale from: 0 to 100; 0 is best.
no estimate extracted3 studies · 351 participantsHigh
Overall quality of Life (EQ5D) Scale from: 0 to 1; 1 is best.
no estimate extracted3 studies · 285 participantsModerate
Downgraded: risk of bias, imprecision, publication bias
Participant global assessment of success (People perceived their pain as better)
RR 1.4 [0.67, 2.95]1 study · 78 participantsModerate
Downgraded: risk of bias, imprecision, publication bias
Incident symptomatic vertebral fractures
RR 1.29 [0.46, 3.62]6 studies · 840 participantsLow
Downgraded: risk of bias, imprecision, publication bias
Other serious adverse events
RR 0.61 [0.33, 1.1]5 studies · 821 participantsLow
Downgraded: risk of bias, imprecision, publication bias