Cochrane · systematic review · CD006349
Percutaneous vertebroplasty for osteoporotic vertebral compression fracture
Buchbinder, R, Johnston, RV, Rischin, KJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 2 · 28.6%High 3 · 42.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyVertebroplasty for osteoporotic vertebral compression fracture
Population: people with osteoporotic vertebral compression fracture
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain Scale from: 0 to 10, 0 is no pain. | no estimate extracted | 5 studies · 535 participants | High |
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. | no estimate extracted | 4 studies · 472 participants | High |
Disease‐specific quality of Life (QUALEFFO) Scale from: 0 to 100; 0 is best. | no estimate extracted | 3 studies · 351 participants | High |
Overall quality of Life (EQ5D) Scale from: 0 to 1; 1 is best. | no estimate extracted | 3 studies · 285 participants | Moderate Downgraded: risk of bias, imprecision, publication bias |
Participant global assessment of success (People perceived their pain as better) | RR 1.4 [0.67, 2.95] | 1 study · 78 participants | Moderate Downgraded: risk of bias, imprecision, publication bias |
Incident symptomatic vertebral fractures | RR 1.29 [0.46, 3.62] | 6 studies · 840 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Other serious adverse events | RR 0.61 [0.33, 1.1] | 5 studies · 821 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Vertebroplasty for osteoporotic vertebral compression fracture
Population: people with osteoporotic vertebral compression fracture
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain Scale from: 0 to 10, 0 is no pain. | no estimate extracted | 5 studies · 535 participants | High |
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. | no estimate extracted | 3 studies · 296 participants | High |
Disease‐specific quality of Life (QUALEFFO) Scale from: 0 to 100; 0 is best. | no estimate extracted | 2 studies · 175 participants | Moderate Downgraded: imprecision, publication bias |
Overall quality of Life (EQ5D) Scale from: 0 to 1; 1 is best. | no estimate extracted | 3 studies · 285 participants | Moderate Downgraded: imprecision, publication bias |
Participant global assessment of success (People perceived their pain as better) | RR 1.4 [0.67, 2.95] | 1 study · 78 participants | Moderate Downgraded: imprecision, publication bias |
Incident symptomatic vertebral fractures | RR 1.08 [0.62, 1.87] | 7 studies · 1020 participants | Moderate Downgraded: imprecision, publication bias |
Other serious adverse events | RR 0.64 [0.36, 1.12] | 5 studies · 821 participants | Moderate Downgraded: imprecision, publication bias |
Vertebroplasty for osteoporotic vertebral compression fracture
Population: people with osteoporotic vertebral compression fracture
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain Scale from: 0 to 10, 0 is best. | no estimate extracted | 2 studies · 201 participants | Moderate Downgraded: imprecision |
Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is best. | no estimate extracted | 2 studies · 201 participants | Moderate Downgraded: imprecision |
Disease‐specific quality of Life (QUALEFFO) Scale from: 0 to 100; 0 is best. | no estimate extracted | 1 study · 73 participants | Moderate Downgraded: imprecision |
Overall quality of Life (EQ5D) Scale from: 0 to 1; 1 is best. | no estimate extracted | 2 studies · 201 participants | Moderate Downgraded: imprecision |
Participant global assessment of success (People perceived their pain as better) | RR 1.4 [0.67, 2.95] | 1 study · 78 participants | Moderate Downgraded: imprecision |
Incident vertebral fractures | RR 1.47 [0.39, 5.5] | 3 studies · 281 participants | Moderate Downgraded: imprecision |
Other serious adverse events | RR 1.01 [0.21, 4.85] | 2 studies · 209 participants | Moderate Downgraded: imprecision |