What do systematic reviews say?

Dornase alfa vs dornase alfa and mannitol

Dornase alfa may leads to higher change in quality of life ‐ CFQ‐R at 3 months compared with dornase alfa and mannitol (low certainty).

• Dornase alfa for cystic fibrosis 2021 · Cochrane Headline outcomes only
  MD 10.61 [0.27, 20.95]
  231 participants
  Low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

The review found no eligible studies for this question.

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nonabsorbable tacks vs fibrin sealant

• Mesh fixation techniques in primary ventral or incisional hernia repair 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Absorbable tacks vs fibrin sealant

• Mesh fixation techniques in primary ventral or incisional hernia repair 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Phaco‐AIT vs Phaco‐Trab

The review found no eligible studies for this question.

• Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Kinesiotaping vs sham taping

The review found no eligible studies for this question.

• Kinesio taping for rotator cuff disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

The review found no eligible studies for this question.

• Ab interno supraciliary microstent surgery for open‐angle glaucoma 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Digital intervention with or without routine supported self‐management vs control

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 123 participants
  Low

NB‐UVB vs PUVA

The review found no eligible studies for this question.

• Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

UVA1 vs PUVA

The review found no eligible studies for this question.

• Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NB‐UVB vs placebo

The review found no eligible studies for this question.

• Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Clinical examination with 24-month recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 6-month recall (high certainty).

• Recall intervals for oral health in primary care patients 2020 · Cochrane All outcomes

  4 years
  MD -0.24 [-1.55, 1.07]
  1 study · 305 participants
  High

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Clinical examination with risk-based recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 24-month recall (high certainty).

• Recall intervals for oral health in primary care patients 2020 · Cochrane All outcomes

  4 years
  MD -0.37 [-1.69, 0.95]
  1 study · 298 participants
  High

Intervention not reported

The review found no eligible studies for this question.

• Dressings and topical agents for arterial leg ulcers 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Any pessary vs control, waiting list or no active treatment

The review found no eligible studies for this question.

• Pessaries (mechanical devices) for managing pelvic organ prolapse in women 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hydrus microstent vs iStent trabecular micro‐bypass stent

The review found no eligible studies for this question.

• Ab interno trabecular bypass surgery with Schlemm´s canal microstent (Hydrus) for open angle glaucoma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cataract surgery with Hydrus microstent vs cataract surgery alone

The review found no eligible studies for this question.

• Ab interno trabecular bypass surgery with Schlemm´s canal microstent (Hydrus) for open angle glaucoma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical antiseptic vs no treatment

The review found no eligible studies for this question.

• Topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Clinical examination with risk-based recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 6-month recall (high certainty).

• Recall intervals for oral health in primary care patients 2020 · Cochrane All outcomes

  4 years
  MD -0.35 [-1.02, 0.32]
  1 study · 1551 participants
  High

Exercise therapy vs control

The review found no eligible studies for this question.

• Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 44 participants
  Very low