Cochrane · systematic review · CD013055

Topical antiseptics for chronic suppurative otitis media

Head, K, Chong, LY, Bhutta, MF, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

ENTAMSTAR 2: not assessed

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.

Questions

current version

GRADE rated

No studies

Included studies

No studies 4 · 57.1%Ungraded 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Topical antiseptic compared to no treatment for chronic suppurative otitis media

Population: chronic suppurative otitis media

7 questions

Outcome	Effect	Evidence	Status / GRADE
Resolution of ear discharge (between 1 week and up to 2 weeks) ‐ not reported Topical antiseptic vs no treatment	no estimate extracted	NR	No studies
Resolution of ear discharge (4 weeks or more) Topical antiseptic vs no treatment	RR 1.73 [1.21, 2.47]	1 study · 180 participants	Very low Downgraded: risk of bias, imprecision
Health‐related quality of life ‐ not reported Topical antiseptic vs no treatment	no estimate extracted	NR	No studies
Ear pain (otalgia) or discomfort or local irritation ‐ not reported Topical antiseptic vs no treatment	no estimate extracted	NR	No studies
Hearing Topical antiseptic vs no treatment	no estimate extracted	1 study · 180 participants	Very low Downgraded: risk of bias, imprecision, indirectness
Serious complications ‐ not reported Topical antiseptic vs no treatment	no estimate extracted	NR	No studies
Suspected ototoxicity Topical antiseptic vs no treatment	no estimate extracted	1 study · 180 participants	Very low Downgraded: risk of bias, imprecision, indirectness