What do systematic reviews say?

Trazodone vs placebo

• Pharmacotherapies for sleep disturbances in dementia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Moderate

Melatonin vs placebo

• Pharmacotherapies for sleep disturbances in dementia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 162 participants
  Low

Interdisciplinary enhanced rehabilitation (inpatient and community rehabilitation) vs conventional rehabilitation

The review found no eligible studies for this question.

• Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Interdisciplinary enhanced rehabilitation (inpatient rehabilitation) vs conventional rehabilitation

The review found no eligible studies for this question.

• Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multicomponent educational intervention vs control

The review found no eligible studies for this question.

• Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐component medication monitoring and adjustment intervention vs control

The review found no eligible studies for this question.

• Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐component hydration intervention vs control

The review found no eligible studies for this question.

• Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Discontinuation vs continuation of antipsychotic medication

• Withdrawal versus continuation of long‐term antipsychotic drug use for behavioural and psychological symptoms in older… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 365 participants
  Low

Summary of findings table ‐ DMT vs exercise

• Dance movement therapy for dementia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 136 participants
  Low

Intervention not reported

• Memantine for dementia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 3337 participants
  High

Rosiglitazone plus metformin vs glibenclamide (glyburide) plus metformin

The review found no eligible studies for this question.

• Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Omega‐3 vs placebo

• Omega‐3 fatty acids for the treatment of dementia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 566 participants
  High
• Omega‐3 fatty acids for the treatment of dementia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 202 participants
  High

Vitamin E + vitamin C vs placebo

• Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 256 participants
  Very low

B vitamins vs placebo

• Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 488 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Vitamin E vs placebo

• Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Low

Vitamin D3 vs placebo

• Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Moderate
• Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 918 participants
  Low

Zinc + copper vs placebo

• Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1072 participants
  Moderate

Multivitamin vs control

• Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 5947 participants
  Low
• Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 2324 participants
  Low

Intervention not reported

• Computerised cognitive training for preventing dementia in people with mild cognitive impairment 2019 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 407 participants
  Very low