Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,337 questions · 1,354 findings · 566 reviews

No studies found 307 · 22.7%GRADE not reported 81 · 6%Very low 424 · 31.3%Low 310 · 22.9%Moderate 189 · 14%High 43 · 3.2%

Fluoroquinolone substitution for ethambutol in a standard six month regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes serious adverse events compared with standard regimen (very low certainty).

1 finding from 1 review

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in serious adverse events compared with standard regimen (low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · patients undergoing laparoscopic cholecystectomy.

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Miniport laparoscopic cholecystectomy vs standard port laparoscopic cholecystectomy

Serious adverse events · patients with laparoscopic cholecystectomy.

It is very uncertain whether miniport laparoscopic cholecystectomy changes serious adverse events compared with standard port laparoscopic cholecystectomy (very low certainty).

1 finding from 1 review

Xiongshao capsule (XSC) plus conventional western medicine (CWM) vs Western medicine

Serious adverse events · patients with restenosis after percutaneous coronary intervention in coronary heart disease

Xiongshao capsule (XSC) plus conventional western medicine (CWM) leads to lower serious adverse events compared with conventional western medicine (CWM) (high certainty).

1 finding from 1 review

Xiongshao capsule (XSC) plus conventional western medicine (CWM) vs conventional western medicine (CWM) plus placebo

Serious adverse events · patients with restenosis after percutaneous coronary intervention in coronary heart disease

Xiongshao capsule (XSC) plus conventional western medicine (CWM) leads to lower serious adverse events compared with conventional western medicine (CWM) plus placebo (high certainty).

1 finding from 1 review

Pregabalin vs placebo at end of treatment

Serious adverse events · patients with fibromyalgia

Pregabalin showed no clear difference in serious adverse events compared with placebo at end of treatment (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · People with giardiasis infection
1 finding from 1 review

Intervention not reported

Serious adverse events · People with giardiasis infection
1 finding from 1 review