Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,337 questions · 1,354 findings · 566 reviews

No studies found 307 · 22.7%GRADE not reported 81 · 6%Very low 424 · 31.3%Low 310 · 22.9%Moderate 189 · 14%High 43 · 3.2%

Laparoscopic fundoplication vs medical management

Serious adverse events · Patients with gastro‐oesophageal reflux disease (GORD) in adults

It is very uncertain whether laparoscopic fundoplication changes serious adverse events compared with medical management (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events

The review found no eligible studies for this question.

1 finding from 1 review

High‐dose corticosteroids vs moderate‐dose or no corticosteroids

Serious adverse events · adults with metastatic extradural spinal cord compression (without peptic ulceration or infection; mixed prognosis)

High‐dose corticosteroids probably leads to higher serious adverse events compared with moderate‐dose or no corticosteroids (moderate certainty).

1 finding from 1 review