Cochrane · systematic review · CD012329

Oxycodone for pain in fibromyalgia in adults

Gaskell, H, Moore, RA, Derry, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Oxycodone compared with placebo for fibromyalgia

Population: adults with fibromyalgia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved
Oxycodone vs placebo
no estimate extractedNRVery low
Substantial benefit: At least 50% reduction in pain, or PGIC much improved
Oxycodone vs placebo
no estimate extractedNRVery low
Lack of efficacy withdrawal
Oxycodone vs placebo
no estimate extractedNRVery low
Adverse event withdrawal
Oxycodone vs placebo
no estimate extractedNRVery low
Serious adverse events
Oxycodone vs placebo
no estimate extractedNRVery low
Deaths
Oxycodone vs placebo
no estimate extractedNRVery low