Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

114 questions · 115 findings · 59 reviews · Metabolic and Endocrine Disorders

No studies found 32 · 27.8%GRADE not reported 4 · 3.5%Very low 33 · 28.7%Low 37 · 32.2%Moderate 7 · 6.1%High 2 · 1.7%

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · healthy physicians

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review