Cochrane · systematic review · CD015385

Thermal stability and storage of human insulin

Richter, B, Bongaerts, B, Metzendorf, M-I · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
1
No studies
6
Included studies
NR
No studies 6 · 85.7%Ungraded 0 · 0%Very low 1 · 14.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Clinical studies

Population: healthy physicians
7 questions
OutcomeEffectEvidenceStatus / GRADE
Potency/bioactivity parameters of human insulin
no estimate extractedNRNo studies
Diabetic ketoacidosis
no estimate extractedNRNo studies
Hypoglycaemic episodes
no estimate extractedNRNo studies
Adverse events
no estimate extractedNRNo studies
Health‐related quality of life
no estimate extractedNRNo studies
HbA1c
no estimate extractedNRNo studies
Mean fall in plasma glucose levels (mmol/L/min)
no estimate extracted1 study · 8 participantsVery low
Downgraded: risk of bias, imprecision, indirectness