Cochrane · systematic review · CD010888
Aromatase inhibitors for short stature in male children and adolescents
McGrath, N, O'Grady, MJ · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Aromatase inhibitors for short stature in male children and adolescents
Population: male children and adolescents with short stature
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Final height | no estimate extracted | NR | No studies |
Near‐final height | no estimate extracted | NR | No studies |
Cognitive outcomes WISC‐III test (verbal performance similarities, comprehension, block design); visuospatial performance; Rey‐Osterrieth test (complex figure copying task) | no estimate extracted | 1 study · 28 participants | Low Downgraded: imprecision |
All‐cause mortality | no estimate extracted | NR | No studies |
Health‐related quality of life | no estimate extracted | NR | No studies |
Adverse events | no estimate extracted | 3 studies · 174 participants | Moderate Downgraded: imprecision |
Socioeconomic effects | no estimate extracted | NR | No studies |