Bisphosphonates vs control
- Bisphosphonates for osteoporosis in people with cystic fibrosis 2023 · Cochrane Headline outcomes onlyno estimate extracted7 studies · 206 participantsModerate
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It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).
Glutamate modulators showed no clear difference in tolerability of treatment ‐ dropouts due to adverse eventscDropout… compared with placebo (low certainty).
SSRIs showed no clear difference in tolerability of treatment ‐ dropouts due to adverse eventseDropout… compared with placebo (low certainty).
It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).
It is very uncertain whether long‐term red cell transfusion changes serious adverse events as a result of sickle cell‐related… compared with hydroxyurea and phlebotomy (very low certainty).
It is very uncertain whether long‐term red cell transfusion changes serious adverse events as a result of sickle cell‐related… compared with hydroxyurea and phlebotomy (very low certainty).
Long‐term red cell transfusion may leads to lower serious adverse events as a result of sickle cell‐related… compared with no transfusion (low certainty).
It is very uncertain whether enteral changes adverse events: pneumonia (as reported by study authors at end of… compared with enteral and parenteral nutrition (very low certainty).
Enteral showed no clear difference in adverse events: pneumonia (as reported by study authors at end of… compared with parenteral nutrition (low certainty).
It is very uncertain whether zoledronate changes number of participants who withdrew due to adverse events… compared with pamidronate or risedronate (very low certainty).
Neonatal vitamin A supplementation showed no clear difference in adverse events during first 48‐72 hours post supplementation ‐… compared with control (high certainty).
Laparoscopic myomectomy showed no clear difference in perioperative in‐hospital adverse events; unscheduled return to… compared with open myomectomy (all types) (low certainty).
Recombinant zoster vaccine probably leads to higher participants with adverse events ‐ any systemic symptomClinical… compared with placebo (moderate certainty).
It is very uncertain whether diclofenac changes serious adverse events during study period № of participants: 60 (1… compared with paracetamol (very low certainty).