Question · asked by 1 review

TCAs with predominantly SRI actions vs placebo: Dropouts due to adverse events

It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
TCAs with predominantly SRI actions vs placebo
Tolerability of treatment ‐ dropouts due to adverse eventsdDropout rate · adults with trichotillomania
It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).
Pharmacotherapy for trichotillomania (2021) · Cochrane Headline outcomes only
RR 4.45 [0.27, 73.81]1 study · 16 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacotherapy for trichotillomania
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.