Cochrane · systematic review · CD005582

Corticosteroids for preventing postherpetic neuralgia

Jiang, X, Li, Y, Chen, N, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Neuromuscular3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 3 versions

Corticosteroids for acute herpes zoster to prevent postherpetic neuralgia

Population: people with acute herpes zoster (within 7 days of onset of rash)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Presence of PHN 6 months after the onset of acute herpetic rashClinical manifestation
RR 0.95 [0.45, 1.99]2 studies · 114 participantsVery low
Downgraded: risk of bias, imprecision
Serious adverse eventsClinical manifestation and laboratory examination
RR 1.65 [0.51, 5.29]5 studies · 755 participantsVery low
Downgraded: risk of bias, imprecision
Non‐serious adverse eventsClinical manifestation and laboratory examination
RR 1.3 [0.9, 1.87]5 studies · 755 participantsLow
Downgraded: risk of bias, imprecision