Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Mirtazapine vs placebo

Withdrawals due to adverse events · adults with fibromyalgia

Mirtazapine showed no clear difference in tolerability: withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Overt hepatic encephalopathy ( · people with hepatic encephalopathy

The intervention may leads to lower adverse events ‐ Overt hepatic encephalopathy ( (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ Overt hepatic encephalopathy ( · people with hepatic encephalopathy

It is very uncertain whether the intervention changes adverse events ‐ Overt hepatic encephalopathy ( (very low certainty).

1 finding from 1 review

Laser ablation vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether laser ablation changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Transarterial embolisation plus radiofrequency ablation vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether transarterial embolisation plus radiofrequency ablation changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Transarterial embolisation plus percutaneous alcohol injection vs percutaneous alcohol injection

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether transarterial embolisation plus percutaneous alcohol injection changes serious adverse events (number of participants) compared with percutaneous alcohol injection (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Botulinum neurotoxin B vs placebo

Withdrawals due to adverse events · adults with cervical dystonia

Botulinum neurotoxin B showed no clear difference in proportion of withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events: Acupuncture versus no treatment · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Biofeedback vs usual care

Adverse events post‐intervention ‐ not reported · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Mindfulness vs usual care

Adverse events post‐intervention ‐ not reported · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Relaxation vs usual care

Adverse events post‐intervention ‐ not reported · patients with fibromyalgia

The review found no eligible studies for this question.

1 finding from 1 review

Evening vs morning dosing regimen

Withdrawals due to adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes withdrawals from treatment due to adverse events compared with morning dosing regimen (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Withdrawals due to adverse events · inactive EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events 12 to 50 weeks compared with placebo (low certainty).

1 finding from 1 review