Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Vitamin A vs placebo

Adverse events: minor gastrointestinal symptoms · healthy people and healthy male physicians

Vitamin A leads to higher adverse events: minor gastrointestinal symptoms compared with placebo (high certainty).

1 finding from 1 review

Regular formoterol and ICS vs same‐dose ICS

Asthma‐related non‐fatal serious adverse events · adults, chronic asthma: all‐cause mortality

Regular formoterol and ICS showed no clear difference in asthma‐related non‐fatal serious adverse events compared with same‐dose ICS (moderate certainty).

1 finding from 1 review

Regular formoterol and ICS vs same‐dose ICS

Asthma‐related non‐fatal serious adverse events · children and adolescents with chronic asthma

It is very uncertain whether regular formoterol and ICS changes asthma‐related non‐fatal serious adverse events compared with same‐dose ICS (very low certainty).

1 finding from 1 review