Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Usual care vs immunosuppressive withdrawal after monotherapy

Withdrawals due to adverse events · Participants with Crohn's disease in remission

It is very uncertain whether usual care changes withdrawal due to adverse events compared with immunosuppressive withdrawal after monotherapy (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy vs control

Withdrawals due to adverse events · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

It is very uncertain whether antihypertensive drug therapy changes withdrawal due to adverse events compared with control (very low certainty).

1 finding from 1 review

Hand exercise vs no exercise

Withdrawals due to adverse events · patients with hand osteoarthritis

It is very uncertain whether hand exercise changes withdrawal due to adverse events compared with no exercise (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events Post‐intervention · adults with stroke
1 finding from 1 review

Honey vs topical antibiotics

Adverse events: honey versus SSD · people with burns

It is very uncertain whether honey changes adverse events: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.2 [0.01, 3.97]
    3 studies · 250 participants
    Very low

Bortezomib vs no bortezomib

Thrombocytopenia · All patients with a diagnosis of multiple myeloma

Bortezomib may leads to higher adverse Events: Thrombocytopenia compared with no bortezomib (low certainty).

3 findings from 1 review

Bortezomib vs no bortezomib

Adverse Events: Infections (All) · All patients with a diagnosis of multiple myeloma

Bortezomib probably leads to higher adverse Events: Infections (All) compared with no bortezomib (moderate certainty).

1 finding from 1 review