Antihypertensive drug therapy vs control: Withdrawals due to adverse events
- Population
- adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
- Intervention
- Antihypertensive drug therapy
- Comparison
- control
- Outcome
- Withdrawals due to adverse events
It is very uncertain whether antihypertensive drug therapy changes withdrawal due to adverse events compared with control (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihypertensive drug therapy vs control Withdrawal due to adverse events · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension) It is very uncertain whether antihypertensive drug therapy changes withdrawal due to adverse events compared with control (very low certainty). Pharmacotherapy for hypertension in adults aged 18 to 59 years (2017) · Cochrane Headline outcomes only | RR 4.82 [1.67, 13.92] | 3 studies · 1223 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapy for hypertension in adults aged 18 to 59 years 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Antihypertensive drug therapy vs placebo or no treatment · adults (18 years of age or older) with hypertension‐induced left ventricular hypertrophy · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.