Findings

What do systematic reviews say?

4,918 questions · 5,537 findings · 1,803 reviews

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No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

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Molteno implant vs Schocket shunt

Adverse events up to 1‐year · People with glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Aqueous shunts for glaucoma 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous shunts vs trabeculectomy

Adverse events up to 1‐year · People with glaucoma

It is very uncertain whether aqueous shunts changes adverse events up to 1‐year compared with trabeculectomy (very low certainty).

1 finding from 1 review

Aqueous shunts for glaucoma 2017 · Cochrane Headline outcomes only
RR 0.59 [0.43, 0.81]
1 study · 212 participants
Very low

Ceftriaxone vs long‐acting (oily) Chloramphenicol compared

Adverse events ‐ short term · people suspected to have meningococcal disease (adults and children)

1 finding from 1 review

Pre‐admission antibiotics for suspected cases of meningococcal disease 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

Topical NSAIDs vs control

Adverse drug events · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes drug‐related adverse events compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 2.95 [0.32, 27.6]
2 studies · 163 participants
Very low

foam dressing vs basic wound contact dressing

Adverse effect/event: 2. Adverse effects ‐ any ‐ medium‐termonly · people of any age with an existing pressure ulcer of Category/Stage II or above

Foam dressings showed no clear difference in adverse events, medium‐term compared with basic contact dressings (low certainty).

1 finding from 1 review

Foam dressings for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 0.58 [0.33, 1.05]
1 study · 95 participants
Low

Intervention not reported

Severe adverse events: rash · antiretroviral‐naïve individuals

The intervention showed no clear difference in severe adverse events: rash (moderate certainty).

1 finding from 1 review

Efavirenz or nevirapine in three‐drug combination therapy with two nucleoside or nucleotide‐reverse transcriptase… 2016 · Cochrane Headline outcomes only
RR 0.58 [0.34, 1]
7 studies · 2277 participants
Moderate

Laparoscopic vs open transhiatal oesophagectomy

Adverse events (proportion) · patients with oesophageal cancer

It is very uncertain whether laparoscopic changes adverse events (proportion) compared with open transhiatal oesophagectomy (very low certainty).

1 finding from 1 review

Laparoscopic versus open transhiatal oesophagectomy for oesophageal cancer 2016 · Cochrane Headline outcomes only
RR 0.64 [0.48, 0.86]
3 studies · 213 participants
Very low

Laparoscopic distal pancreatectomy vs open distal pancreatectomy

Adverse events (proportion) · patients with pancreatic cancer

It is very uncertain whether laparoscopic distal pancreatectomy changes adverse events (proportion) compared with open distal pancreatectomy (very low certainty).

1 finding from 1 review

Laparoscopic versus open distal pancreatectomy for pancreatic cancer 2016 · Cochrane Headline outcomes only
OR 0.95 [0.54, 1.66]
4 studies · 246 participants
Very low

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Adverse events (proportion) · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes adverse events (proportion) compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis 2016 · Cochrane Headline outcomes only
RR 0.55 [0.22, 1.35]
4 studies · 226 participants
Very low

Intervention not reported

Any adverse events 49 weeks · adults with asthma

The intervention leads to lower any adverse events 49 weeks (high certainty).

1 finding from 1 review

Long‐acting muscarinic antagonists (LAMA) added to combination long‐acting beta₂‐agonists and inhaled corticosteroids… 2016 · Cochrane Headline outcomes only
OR 0.7 [0.52, 0.94]
3 studies · 1197 participants
High

Intervention not reported

Adverse events/side effects · participants with an exacerbation of COPD; people with asthma excluded from our analysis

The intervention showed no clear difference in adverse events/side effects (low certainty).

1 finding from 1 review

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD 2016 · Cochrane Headline outcomes only
OR 1.65 [0.42, 6.48]
3 studies · 110 participants
Low

Additional radon in carbon dioxide baths vs carbon dioxide baths only

Adverse events Not reported · patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Balneotherapy (or spa therapy) for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Balneotherapy vs drug treatment

Adverse events Not reported · patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Balneotherapy (or spa therapy) for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Balneotherapy vs placebo

Adverse events Not reported · patients with rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Balneotherapy (or spa therapy) for rheumatoid arthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events Toxic deaths · cancer patients receiving myelotoxic chemotherapy

The intervention showed no clear difference in adverse events Toxic deaths (low certainty).

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
RR 1.32 [0.3, 5.69]
1 study · 115 participants
Low

Fresh frozen plasma vs no treatment

Frequency of adverse events ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for prophylaxis of hepatic veno‐occlusive disease in people undergoing haematopoietic stem cell… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LAMA add‐on vs ICS alone

Any adverse events 24 weeks · adults with asthma not well controlled on ICS

LAMA add‐on showed no clear difference in any adverse events 24 weeks compared with ICS alone (low certainty).

1 finding from 1 review

Long‐acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for… 2015 · Cochrane Headline outcomes only
OR 0.95 [0.8, 1.14]
5 studies · 2562 participants
Low

Massage + phonophoresis vs phonophoresis alone

Adverse events Not measured · patients with extensor carpi radialis tendinitis

The review found no eligible studies for this question.

1 finding from 1 review

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Deep transverse massage + physical therapy vs physical therapy alone

Adverse events Not measured · patients with iliotibial band friction syndrome (knee tendinitis)

The review found no eligible studies for this question.

1 finding from 1 review

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Massage + ultrasound and placebo ointment vs ultrasound + placebo ointment only

Adverse events Not measured · patients with extensor carpi radialis tendinitis

The review found no eligible studies for this question.

1 finding from 1 review

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found