Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Effect of root canal filling techniques and materials on endodontic treatment outcomes: a systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial. Asgary, 2022 · Asgary Saeed, Eghbal Mohammad Jafar, et al. · Clinical oral investigations PMID:34854987 | 2022 | 4 | 2 | not extracted yet |
| Tricyclic antidepressants: therapeutic properties and affinity for alpha-noradrenergic receptor binding sites in the brain. Daniele et al. (2020) · U'Prichard D C, Greenberg D A, et al. · Science (New York, N.Y.) PMID:202024 | 1978 | 4 | none stated | not extracted yet |
| Chen 2016 matched by author and year (probable) | NR | 4 | 2 | not extracted yet |
| Kumar 2020 matched by author and year (probable) | NR | 3 | none stated | not extracted yet |
| Association between the irrigation-agitation techniques and Periapical Healing of large periapical lesions: a Randomized Controlled Trial. Dogan 2024 · Doğan Mehmet Umutcan, Arıcıoğlu Banu, et al. · Clinical oral investigations PMID:38878107 | 2024 | 2 | 1 | not extracted yet |
| Outcome of root canal treatment using warm vertical compaction with bioceramic and resin-based sealers: A randomised clinical trial. Hu 2023 · Hu Jinghao, Zhu Yunjie, et al. · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc PMID:36378149 | 2023 | 2 | 1 | not extracted yet |
| Evaluation of postoperative pain and healing following regenerative endodontics using platelet-rich plasma versus conventional endodontic treatment… Ahmed 2023 · Ahmed Yassmin Elsayed, Ahmed Geraldine Mohamed, et al. · International endodontic journal PMID:36565044 | 2023 | 2 | 1 | not extracted yet |
| A Randomized Controlled Clinical Trial of Pulpotomy versus Root Canal Therapy in Mature Teeth with Irreversible Pulpitis: Outcome, Quality of Life,… Taha 2023 · Taha Nessrin A, Abuzaid Alaa M, et al. · Journal of endodontics PMID:37080387 | 2023 | 2 | none stated | not extracted yet |
| Effect of Endodontic Sealer in Young Molars Treated by Undergraduate Students - A Randomized Clinical Trial. Cunha 2020 · Cunha Suely Aparecida, Soares Carlos José, et al. · Brazilian dental journal PMID:33237229 | 2020 | 2 | 1 | not extracted yet |
| Effect of Different Concentrations of Sodium Hypochlorite on Outcome of Primary Root Canal Treatment: A Randomized Controlled Trial. Verma 2019 · Verma Neha, Sangwan Pankaj, et al. · Journal of endodontics PMID:30827769 | 2019 | 2 | 3 | not extracted yet |
| Regenerative Endodontics Versus Apexification in Immature Permanent Teeth with Apical Periodontitis: A Prospective Randomized Controlled Study. Lin 2017 · Lin Jiacheng, Zeng Qian, et al. · Journal of endodontics PMID:28864219 | 2017 | 2 | 3 | not extracted yet |
| Radiographic healing after a root canal treatment performed in single-rooted teeth with and without ultrasonic activation of the irrigant: a… Liang 2013 · Liang Yu-Hong, Jiang Lei-Meng, et al. · Journal of endodontics PMID:24041381 | 2013 | 2 | 1 | not extracted yet |
| Ahmed et al 2023 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Asgary et al. 2022 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Bardini et al. 2021 matched by author and year (probable) | NR | 2 | 1 | not extracted yet |
| Mendoza et al. 2010 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Tang et al. 2015 matched by author and year (probable) | NR | 2 | none stated | not extracted yet |
| Verma et al. 2019 matched by author and year (probable) | NR | 2 | 2 | not extracted yet |
| A 4-year follow-up of root canal obturation using a calcium silicate-based sealer and a zinc oxide-eugenol sealer: A randomized clinical trial. Bardini 2021 · Bardini Giulia, Bellido Montse Mercade, et al. · International endodontic journal PMID:39655615 | 2025 | 1 | none stated | not extracted yet |
| Clinical and radiographic outcome of a bioceramic sealer compared to a resin-based sealer: a retrospective study. Bani-Younes 2025 · Bani-Younes Hamzah Ahmad, Methqal Karina Abdelaziz, et al. · Scientific reports PMID:40369057 | 2025 | 1 | none stated | not extracted yet |
| Clinical efficacy of root canal treatment at 2 years using a new ready-to-use injectable calcium silicate-based sealer: A multicentric randomised… Simnon 2025 · Simon Stéphane, Beauquis Julien, et al. · International endodontic journal PMID:40491343 | 2025 | 1 | none stated | not extracted yet |
| The Outcome of Nonsurgical Root Canal Treatment Using Sealer-based Obturation versus Warm Vertical Compaction: A Randomized Controlled Trial. Alzoubi 2025 · Alzoubi Fahad, Alajmi Samhan, et al. · Journal of endodontics PMID:40653155 | 2025 | 1 | none stated | not extracted yet |
| Posterior partial crowns out of lithium disilicate with or without posts: A randomized controlled study at 9 years follow up. Cagidiaco 2025 · Ferrari Cagidiaco Edoardo, Verniani Giulia, et al. · Journal of dentistry PMID:40738215 | 2025 | 1 | none stated | not extracted yet |
| Outcome of Nonsurgical Root Canal Retreatment of Teeth with Persistent Apical Periodontitis Treated with Foraminal Enlargement and 2% Chlorhexidine… Baltieri 2024 · Baltieri Patrick Wilson Quelis, de Araújo Lucas Peixoto, et al. · Journal of endodontics PMID:39313095 | 2024 | 1 | none stated | not extracted yet |
| The effect of two different root canal sealers on treatment outcome and post-obturation pain in single-visit root canal treatment: A prospective… Coşar 2023 · Coşar Melis, Kandemir Demirci Gözde, et al. · International endodontic journal PMID:36385378 | 2023 | 1 | none stated | not extracted yet |
| The Use of Premixed Calcium Silicate Bioceramic Sealer with Warm Carrier-Based Technique: A 2-Year Study for Patients Treated in a Master Program. Zamparini 2023 · Zamparini Fausto, Spinelli Andrea, et al. · Journal of functional biomaterials PMID:36976088 | 2023 | 1 | none stated | not extracted yet |
| Outcome of Root Canal Treatment of Teeth with Asymptomatic Apical Periodontitis Treated with Foraminal Enlargement and 2% Chlorhexidine Gel: A… Silva 2023 · da Silva Tamares Andrade, de Araújo Lucas Peixoto, et al. · Journal of endodontics PMID:37307870 | 2023 | 1 | none stated | not extracted yet |
| Clinical Efficacy of Sealer-based Obturation Using Calcium Silicate Sealers: A Randomized Clinical Trial. Kim 2022 · Kim Ji-Hyung, Cho Sin-Yeon, et al. · Journal of endodontics PMID:34856212 | 2022 | 1 | none stated | not extracted yet |
| Outcome of single- versus two-visit root canal retreatment in teeth with periapical lesions: A randomized clinical trial. Karaoğlan 2022 · Karaoğlan Fulya, Miçooğulları Kurt Seniha, et al. · International endodontic journal PMID:35488883 | 2022 | 1 | none stated | not extracted yet |
| USAGE OF CHLORHEXIDINE AS A FINAL IRRIGANT IN ONE-VISIT ROOT CANAL TREATMENT IN COMPARISON WITH CONVENTIONAL TWO-VISIT ROOT CANAL TREATMENT IN… Kurt 2018 · Kurt Seniha Miçooğulları, Demirci Gözde Kandemir, et al. · The journal of evidence-based dental practice PMID:36162893 | 2022 | 1 | none stated | not extracted yet |
| Clinical Outcome of Nonsurgical Root Canal Treatment Using a Matched Single-Cone Obturation Technique with a Calcium Hydroxide-based Sealer:… Subbiya 2022 · Subbiya Arunajatesan, Kishen Anil, et al. · Journal of endodontics PMID:36191866 | 2022 | 1 | none stated | not extracted yet |
| Outcome Assessment of Teeth with Necrotic Pulps and Apical Periodontitis Treated with Long-term Calcium Hydroxide. Best 2021 · Best Sheldon, Ammons Christopher L, et al. · Journal of endodontics PMID:32950557 | 2021 | 1 | none stated | not extracted yet |
| Combination of Nonsurgical Endodontic and Vital Pulp Therapy for Management of Mature Permanent Mandibular Molar Teeth with Symptomatic Irreversible… Koli 2021 · Koli Bhawna, Chawla Amrita, et al. · Journal of endodontics PMID:33091455 | 2021 | 1 | none stated | not extracted yet |
| Retrospective clinical evaluation of root canal treatment with or without photodynamic therapy for necrotic teeth and teeth subjected to retreatment. Conejero 2021 · Conejero María-José, Almenar Amelia, et al. · Journal of oral science PMID:33731503 | 2021 | 1 | none stated | not extracted yet |
| Effect of Apical Third Enlargement to Different Preparation Sizes and Tapers on Postoperative Pain and Outcome of Primary Endodontic Treatment: A… Fatima 2021 · Fatima Shazra, Kumar Ashok, et al. · Journal of endodontics PMID:34058250 | 2021 | 1 | none stated | not extracted yet |
| Prognostic validity of the Periapical and Endodontic Status Scale for the radiographically assessed 2-year treatment outcomes in teeth with apical… Gudac 2021 · Gudac Jelena, Hellén-Halme Kristina, et al. · BMC oral health PMID:34281553 | 2021 | 1 | none stated | not extracted yet |
| Retrospective fractal analyses of one-year follow-up data obtained after single-visit nonsurgical endodontic retreatment on periapical radiographs. Tosun 2021 · Tosun Samet, Karataslioglu Emrah, et al. · Clinical oral investigations PMID:34302217 | 2021 | 1 | none stated | not extracted yet |
| The impact of an enhanced infection control protocol on molar root canal treatment outcome - a randomized clinical trial. Zahran 2021 · Zahran Shatha, Patel Shanon, et al. · International endodontic journal PMID:34352123 | 2021 | 1 | none stated | not extracted yet |
| A prospective cohort study evaluating the outcome of root canal retreatment in symptomatic mandibular first molars with periapical lesions. Serefoglu 2021 · Serefoglu Burcu, Miçooğulları Kurt Seniha, et al. · International endodontic journal PMID:34516682 | 2021 | 1 | none stated | not extracted yet |
| The effect of an intraorifice barrier and base under coronal restorations on the healing of apical periodontitis: a randomized controlled trial. Kumar 2020 · Kumar G, Tewari S, et al. · International endodontic journal PMID:31587317 | 2020 | 1 | none stated | not extracted yet |
| Effectiveness of a reciprocating single file, single cone endodontic treatment approach: a randomized controlled pragmatic clinical trial. Figueiredo 2020 · de Figueiredo Fabricio Eneas Diniz, Lima Laila F, et al. · Clinical oral investigations PMID:31650315 | 2020 | 1 | none stated | not extracted yet |
| The fate of root canals obturated with Thermafil: 10-year data for patients treated in a master's program. Chiara 2019 · Pirani Chiara, Zamparini Fausto, et al. · Clinical oral investigations PMID:30519823 | 2019 | 1 | none stated | not extracted yet |
| Outcome of Endodontic Retreatment Using 2 Root Canal Irrigants and Influence of Infection on Healing as Determined by a Molecular Method: A… Zandi 2019 · Zandi Homan, Petronijevic Nikola, et al. · Journal of endodontics PMID:31300248 | 2019 | 1 | none stated | not extracted yet |
| Success of maintaining apical patency in teeth with periapical lesion: a randomized clinical study. Arslan 2019 · Arslan Hakan, Doğanay Yıldız Ezgi, et al. · Quintessence international (Berlin, Germany : 1985) PMID:31463482 | 2019 | 1 | none stated | not extracted yet |
| Healing of Periapical Lesions after Endodontic Treatment with the GentleWave Procedure: A Prospective Multicenter Clinical Study. Sigurdsson 2018 · Sigurdsson Asgeir, Garland Randy W, et al. · Journal of endodontics PMID:29336878 | 2018 | 1 | none stated | not extracted yet |
| Clinical Outcome of Non-Surgical Root Canal Treatment Using a Single-cone Technique with Endosequence Bioceramic Sealer: A Retrospective Analysis. Elizabeth 2018 · Chybowski Elizabeth A, Glickman Gerald N, et al. · Journal of endodontics PMID:29606401 | 2018 | 1 | none stated | not extracted yet |
| Comparison of ozone gas and sodium hypochlorite/chlorhexidine two-visit disinfection protocols in treating apical periodontitis: a randomized… Kist 2017 · Kist Stefan, Kollmuss Maximilian, et al. · Clinical oral investigations PMID:27173580 | 2017 | 1 | none stated | not extracted yet |
| A prospective study assessing the effect of coronal tooth structure loss on the outcome of root canal retreatment. Al-nuaimi 2017 · Al-Nuaimi N, Patel S, et al. · International endodontic journal PMID:28294354 | 2017 | 1 | none stated | not extracted yet |
| Healing of Apical Periodontitis after Nonsurgical Treatment in Patients with Type 2 Diabetes. Arya 2017 · Arya Suman, Duhan Jigyasa, et al. · Journal of endodontics PMID:28803674 | 2017 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Postoperative Pain and Success Rate after Pulpotomy and Root Canal Treatment in Cariously Exposed Mature Permanent Molars:… Galani 2017 · Galani Mohit, Tewari Sanjay, et al. · Journal of endodontics PMID:29061359 | 2017 | 1 | none stated | not extracted yet |