Primary study · included by 2 reviews

Regenerative Endodontics Versus Apexification in Immature Permanent Teeth with Apical Periodontitis: A Prospective Randomized Controlled Study.

Lin 2017 · Lin Jiacheng, Zeng Qian, Wei Xi, et al. · Journal of endodontics · 2017

Included by

Effect of root canal filling techniques and materials on endodontic treatment outcomes: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Lin 2017 · Table 2; reference 45

The review does not say which of its outcomes this study informs.

Association of Apical Maturity With Clinical and Biological Outcomes After Regenerative Endodontic Procedures: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Lin 2017 · Table 1; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Tooth survival rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.98 [0.96, 0.99]	9 studies · 453 participants	GRADE not reported
Complete apical closure rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.53 [0.36, 0.70]	4 studies · 196 participants	GRADE not reported
Tooth survival rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.98 [0.95, 0.99]	9 studies · 453 participants	GRADE not reported
Complete apical closure rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.57 [0.50, 0.64]	4 studies · 196 participants	GRADE not reported
Clinical success rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.90 [0.83, 0.95]	10 studies · 496 participants	GRADE not reported
Clinical success rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.89 [0.86, 0.91]	10 studies · 496 participants	GRADE not reported

2 including reviews in total.