evidencegaps
Primary study · included by 2 reviews

Association between the irrigation-agitation techniques and Periapical Healing of large periapical lesions: a Randomized Controlled Trial.

Dogan 2024 · Doğan Mehmet Umutcan, Arıcıoğlu Banu, Köse Taha Emre, et al. · Clinical oral investigations · 2024

Included by

Effect of root canal filling techniques and materials on endodontic treatment outcomes: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Doğan 2024 · Table 2; reference 65

The review does not say which of its outcomes this study informs.

Prognosis of Periapical Lesions Treated by Activated Disinfection (PUI, Laser) Without the Use of Systemic Antibiotics: Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Dogan 2024 · Tables 3 and 4; references 22-26
Outcome this study informsPooled effectEvidenceCertainty
Periapical healing (clinical and/or radiographic treatment success)
Activated irrigation (passive ultrasonic irrigation and/or laser-assisted irrigation) vs Conventional syringe and needle irrigation (same irrigant, no systemic antibiotics) · Longest available follow-up (6 to 19 months)
OR 2.25 [1.29, 3.93]5 studies · 451 participantsModerate

2 including reviews in total.