Studies
Primary studies
5,083 studies included by 199 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Comparative evaluation of platelet-rich fibrin, mineral trioxide aggregate, and calcium hydroxide as pulpotomy agents in permanent molars with… Kumar, 2016 · Kumar Varun, Juneja Ruchi, et al. · Contemporary clinical dentistry PMID:27994420 | 2016 | 2 | 1 | not extracted yet |
| Pulpotomy in caries-exposed immature permanent molars using calcium-enriched mixture cement or mineral trioxide aggregate: a randomized clinical… Nosrat 2012 · Nosrat Ali, Seifi Amir, et al. · International journal of paediatric dentistry PMID:22309243 | 2013 | 2 | 1 | not extracted yet |
| Treatment of post-orthodontic white spot lesions with casein phosphopeptide-stabilised amorphous calcium phosphate Brochner 2011 · Bröchner Ann, Christensen Carsten, et al. · Clinical Oral Investigations DOI:10.1007/s00784-010-0401-2 | 2010 | 2 | 1 | not extracted yet |
| Examination of 6 and 12 month follow-up of calcium hydroxide and calcium silicate materials used in direct and indirect pulp capping Yavuz 2025 · YAVUZ YASEMİN, KOTANLI Sedef, et al. · Advances in Clinical and Experimental Medicine DOI:10.17219/acem/194504 | 2025 | 1 | none stated | not extracted yet |
| Examination of 6 and 12 month follow-up of calcium hydroxide and calcium silicate materials used in direct and indirect pulp capping. Yavuz 2025 · Yavuz Yasemin, Kotanli Sedef, et al. · Advances in clinical and experimental medicine : official organ Wroclaw Medical University PMID:39932469 | 2025 | 1 | 1 | not extracted yet |
| Effects of an orthodontic primer containing amorphous fluorinated calcium phosphate nanoparticles on enamel white spot lesions. Xu 2023 · Xu Yuedan, Sun Yi, et al. · Journal of the mechanical behavior of biomedical materials PMID:36379092 | 2023 | 1 | 1 | not extracted yet |
| Treatment outcome of partial pulpotomy using two different calcium silicate materials in mature permanent teeth with symptoms of irreversible… Tzanetakis, 2023 · Tzanetakis Giorgos N, Koletsi Despina, et al. · International endodontic journal PMID:37452640 | 2023 | 1 | none stated | not extracted yet |
| Effect of calcium fluoride nanoparticles in prevention of demineralization during orthodontic fixed appliance treatment: a randomized clinical trial Al Tuma et al. 2023 · Al Tuma Rawof R, Yassir Yassir A · European Journal of Orthodontics DOI:10.1093/ejo/cjac055 | 2022 | 1 | 1 | not extracted yet |
| Long‐term evaluation of early‐enamel lesions treated with novel experimental tricalcium silicate paste: A 2‐year randomized clinical trial Hamdi 2022 · Hamdi Kareem, Hamama Hamdi H., et al. · Journal of Esthetic and Restorative Dentistry DOI:10.1111/jerd.12941 | 2022 | 1 | none stated | not extracted yet |
| Outcome of full pulpotomy in mature permanent molars using 3 calcium silicate-based materials: A parallel, double blind, randomized controlled trial. Taha, 2022 · Taha Nessrin A, Al-Rawash Mohanad H, et al. · International endodontic journal PMID:35152464 | 2022 | 1 | none stated | not extracted yet |
| Dentin Biomodification with Flavonoids and Calcium Phosphate Ion Clusters to Improve Dentin Bonding Stability. Paik et al., 2022 · Paik Youna, Kim Jae-Hoon, et al. · Materials (Basel, Switzerland) PMID:35208035 | 2022 | 1 | none stated | not extracted yet |
| Mineral Trioxide Aggregate vs Calcium-Enriched Mixture Pulpotomy in Young Permanent Molars with a Diagnosis of Irreversible Pulpitis: A Randomized… Sharaan, 2022 · Sharaan Marwa, Ali Asmaa · Iranian endodontic journal PMID:36704084 | 2022 | 1 | none stated | not extracted yet |
| Clinical and microbiological evaluation of calcium silicate versus calcium hydroxide in two-step indirect pulp treatment: A randomized clinical trial Bayoumy 2021 · Bayoumy EhsanHossam El-Din, Abi Elhassan MohsenHussien, et al. · Journal of International Oral Health DOI:10.4103/jioh.jioh_33_20 | 2021 | 1 | none stated | not extracted yet |
| Shear bond strength of orthodontic brackets on intact and demineralized enamel after application of resin infiltrant, fluoride varnish and casein… Daneshkazemi et al. 2021 · Daneshkazemi Pedram, Sadeghian Sousan, et al. · International orthodontics PMID:33775598 | 2021 | 1 | none stated | not extracted yet |
| Efficacy of different calcium silicate materials as pulp-capping agents: Randomized clinical trial. Peskersoy 2021 · Peskersoy Cem, Lukarcanin Jusuf, et al. · Journal of dental sciences PMID:33854725 | 2021 | 1 | 1 | not extracted yet |
| Association between Serum Ferritin, Hemoglobin, Vitamin D3, Serum Albumin, Calcium, Thyrotropin-releasing Hormone with Early Childhood Caries: A… Jha et al. 2021 · Jha Anju, Jha Sovendu, et al. · International journal of clinical pediatric dentistry PMID:34934277 | 2021 | 1 | none stated | not extracted yet |
| Comparative assessment of titanium-prepared platelet-rich fibrin, EndoSequence root repair material, and calcium hydroxide as pulpotomy agents in… Doranala, 2021 · Doranala Suryasowjanya, Surakanti Jayaprada Reddy, et al. · Journal of conservative dentistry : JCD PMID:35558675 | 2021 | 1 | none stated | not extracted yet |
| Effectiveness of Self-assembling Peptide P11-4 Compared to Tricalcium Phosphate Fluoride Varnish in Remineralization of White Spot Lesions: A… Kobeissi 2020 · Kobeissi Riham, Badr Sherine By, et al. · International journal of clinical pediatric dentistry PMID:33623327 | 2020 | 1 | none stated | not extracted yet |
| Success of Direct Pulp Capping Using Mineral Trioxide Aggregate and Calcium Hydroxide in Mature Permanent Molars with Pulps Exposed during Carious… Suhag 2019 · Suhag Komal, Duhan Jigyasa, et al. · Journal of Endodontics DOI:10.1016/j.joen.2019.02.025 | 2019 | 1 | none stated | not extracted yet |
| Efficacy of Amorphous Calcium Phosphate (ACP) Containing Adhesive in Preventing Demineralization during Orthodontic Treatment, a Triple Blinded… Alshammari 2019 · Alshammari Fahad Mohammed, Sanea Jamal Al · The Journal of Contemporary Dental Practice DOI:10.5005/jp-journals-10024-2587 | 2019 | 1 | 1 | not extracted yet |
| Success of Direct Pulp Capping Using Mineral Trioxide Aggregate and Calcium Hydroxide in Mature Permanent Molars with Pulps Exposed during Carious… Suhag 2019 · Suhag Komal, Duhan Jigyasa, et al. · Journal of endodontics PMID:31104819 | 2019 | 1 | 1 | not extracted yet |
| Remineralization Potential of Calcium and Phosphate-based Agents and Their Effects on Bonding of Orthodontic Brackets. Uy et al. 2019 · Uy Erika, Ekambaram Manikandan, et al. · The journal of adhesive dentistry PMID:31165104 | 2019 | 1 | none stated | not extracted yet |
| Effects of calcium-containing desensitizers on the bonding stability of an etch-and-rinse adhesive against long-term water storage and pH cycling. Yang et al., 2018 · Yang Hongye, Chen Zhiyong, et al. · Dental materials journal PMID:29176299 | 2018 | 1 | none stated | not extracted yet |
| Antibacterial and remineralizing orthodontic adhesive containing quaternary ammonium resin monomer and amorphous calcium phosphate nanoparticles. Liu 2018 · Liu Yan, Zhang Ling, et al. · Journal of dentistry PMID:29534887 | 2018 | 1 | 1 | not extracted yet |
| Anti-erosive effect of calcium carbonate suspensions. Tirupathi, 2019 · Scandiffio Priscila, Mantilla Tais, et al. · Journal of clinical and experimental dentistry PMID:30305876 | 2018 | 1 | 1 | not extracted yet |
| Direct Pulp Capping with Calcium Hydroxide, Mineral Trioxide Aggregate, and Biodentine in Permanent Young Teeth with Caries: A Randomized Clinical… Brizuela 2017 · Brizuela Claudia, Ormeño Andrea, et al. · Journal of Endodontics DOI:10.1016/j.joen.2017.06.031 | 2017 | 1 | none stated | not extracted yet |
| Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide. Kundzina 2017 · Kundzina R, Stangvaltaite L, et al. · International endodontic journal PMID:27891629 | 2017 | 1 | 1 | not extracted yet |
| No additional benefit of using a calcium hydroxide liner during stepwise caries removal: A randomized clinical trial. Pereira 2017 · Pereira Maria Auxiliadora, Santos-Júnior Reginaldo Batista Dos, et al. · Journal of the American Dental Association (1939) PMID:28343596 | 2017 | 1 | none stated | not extracted yet |
| Direct Pulp Capping with Calcium Hydroxide, Mineral Trioxide Aggregate, and Biodentine in Permanent Young Teeth with Caries: A Randomized Clinical… Brizuela 2017 · Brizuela Claudia, Ormeño Andrea, et al. · Journal of endodontics PMID:28917577 | 2017 | 1 | 1 | not extracted yet |
| Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide Kundzina 2017 · Kundzina R., Stangvaltaite L., et al. · International Endodontic Journal DOI:10.1111/iej.12719 | 2016 | 1 | none stated | not extracted yet |
| Efficacy of a casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste in preventing white spot lesions in patients with fixed orthodontic… Esenlik et al. 2016 · Esenlik E, Uzer Çelik E, et al. · European journal of paediatric dentistry PMID:28045314 | 2016 | 1 | none stated | not extracted yet |
| Efficacy of calcium‐ and fluoride‐containing materials for the remineralization of primary teeth with early enamel lesion Memarpour 2015 · Memarpour Mahtab, Soltanimehr Elham, et al. · Microscopy Research and Technique DOI:10.1002/jemt.22543 | 2015 | 1 | 1 | not extracted yet |
| Clinical and radiographic assessment of the efficacy of calcium silicate indirect pulp capping: a randomized controlled clinical trial. Hashem 2015 · Hashem D, Mannocci F, et al. · Journal of dental research PMID:25710953 | 2015 | 1 | none stated | not extracted yet |
| Efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate for remineralization of primary teeth: a randomized clinical trial. Memarpour 2015 · Memarpour Mahtab, Fakhraei Ebrahim, et al. · Medical principles and practice : international journal of the Kuwait University, Health Science Centre PMID:25895964 | 2015 | 1 | none stated | not extracted yet |
| The effect of two types chewing gum containing casein phosphopeptide-amorphous calcium phosphate and xylitol on salivary Streptococcus mutans. Emamieh et al. 2015 · Emamieh Shila, Khaterizadeh Yosra, et al. · Journal of conservative dentistry : JCD PMID:26069402 | 2015 | 1 | none stated | not extracted yet |
| Casein phosphopeptide–amorphous calcium phosphate remineralization of primary teeth early enamel lesions Zhou 2014 · Zhou Chunhua, Zhang Dongliang, et al. · Journal of Dentistry DOI:10.1016/j.jdent.2013.11.005 | 2014 | 1 | 1 | not extracted yet |
| Randomized control trial comparing calcium hydroxide and mineral trioxide aggregate for partial pulpotomies in cariously exposed pulps of permanent… Chailertvanitkul, 2014 · Chailertvanitkul P, Paphangkorakit J, et al. · International endodontic journal PMID:24299006 | 2014 | 1 | none stated | not extracted yet |
| Protective effect of calcium nanophosphate and CPP-ACP agents on enamel erosion Carvalho 2013 · Carvalho Fabiola Galbiatti de, Brasil Veruska Lima Moura, et al. · Brazilian Oral Research DOI:10.1590/s1806-83242013000600004 | 2013 | 1 | 1 | not extracted yet |
| The effect of casein phosphopeptide amorphous calcium phosphate on the in vitro shear bond strength of orthodontic brackets. Park et al. 2013 · Park Sun-Youn, Cha Jung-Yul, et al. · Korean journal of orthodontics PMID:23504444 | 2013 | 1 | none stated | not extracted yet |
| Comparative evaluation of remineralization potential of casein phosphopeptide-amorphous calcium phosphate and casein phosphopeptide-amorphous… Mehta 2013 · Mehta R, Nandlal B, et al. · Indian journal of dental research : official publication of Indian Society for Dental Research PMID:24552927 | 2013 | 1 | none stated | not extracted yet |
| Pulpotomy in caries‐exposed immature permanent molars using calcium‐enriched mixture cement or mineral trioxide aggregate: a randomized clinical trial Nosrat, 2013 · NOSRAT ALI, SEIFI AMIR, et al. · International Journal of Paediatric Dentistry DOI:10.1111/j.1365-263x.2012.01224.x | 2012 | 1 | 1 | not extracted yet |
| Effects of a fluoride-containing casein phosphopeptide-amorphous calcium phosphate complex on the shear bond strength of orthodontic brackets. Cehreli et al. 2012 · Cehreli Sevi Burçak, Sar Cagla, et al. · European journal of orthodontics PMID:21317209 | 2012 | 1 | none stated | not extracted yet |
| Do enamel microabrasion and casein phosphopeptide-amorphous calcium phosphate affect shear bond strength of orthodontic brackets bonded to a… Baysal and Uysal 2012 · Baysal Asli, Uysal Tancan · The Angle orthodontist PMID:21787200 | 2012 | 1 | none stated | not extracted yet |
| Effects of the Addition of Fluoride and Calcium to Low-Concentrated Carbamide Peroxide Agents on the Enamel Surface and Subsurface Cavalli 2011 · Cavalli Vanessa, Rodrigues Lidiany Karla Azevedo, et al. · Photomedicine and Laser Surgery DOI:10.1089/pho.2010.2797 | 2011 | 1 | 1 | not extracted yet |
| Treatment of post-orthodontic white spot lesions with casein phosphopeptide-stabilised amorphous calcium phosphate. Bröchner 2011 · Bröchner Ann, Christensen Carsten, et al. · Clinical oral investigations PMID:20383545 | 2011 | 1 | none stated | not extracted yet |
| A comparative evaluation of casein phosphopeptide-amorphous calcium phosphate and fluoride on the shear bond strength of orthodontic brackets. Tabrizi and Cakirer 2011 · Tabrizi Anis, Cakirer Banu · European journal of orthodontics PMID:20651043 | 2011 | 1 | none stated | not extracted yet |
| Effects of the addition of fluoride and calcium to low-concentrated carbamide peroxide agents on the enamel surface and subsurface. Cavalli 2011 · Cavalli Vanessa, Rodrigues Lidiany Karla Azevedo, et al. · Photomedicine and laser surgery PMID:21204703 | 2011 | 1 | none stated | not extracted yet |
| Do fluoride and casein phosphopeptide-amorphous calcium phosphate affect shear bond strength of orthodontic brackets bonded to a demineralized… Uysal et al. 2011 · Uysal Tancan, Baysal Asli, et al. · The Angle orthodontist PMID:21261484 | 2011 | 1 | none stated | not extracted yet |
| In vitro properties of orthodontic adhesives with fluoride or amorphous calcium phosphate. Chow 2011 · Chow Clara Ka Wai, Wu Christine D, et al. · International journal of dentistry PMID:21912546 | 2011 | 1 | 1 | not extracted yet |
| Success rate of calcium hydroxide pulpotomy in primary molars restored with amalgam and stainless steel crowns Sonmez and Duruturk 2010 · Sonmez D., Duruturk L. · British Dental Journal DOI:10.1038/sj.bdj.2010.446 | 2010 | 1 | 1 | not extracted yet |