Cochrane Review Group

Metabolic and Endocrine Disorders

84 systematic reviews in Metabolic and Endocrine Disorders ask 1,105 questions. 39.3% have no studies to answer them, 22.3% rest on very low certainty evidence and 14.1% reach moderate or high certainty.

Reviews

Questions

1,105

current versions

No studies

39.3%

Moderate or high

14.1%

No studies 434 · 39.3%Ungraded 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Search questions in Metabolic and Endocrine Disorders

Thinnest evidence

All no studies and very low questions

Question	Effect	Evidence	Status / GRADE
Intervention NR Health‐related quality of life · participants living with overweight or obesity Calcium supplementation for people with overweight or obesity (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR All‐cause mortality · participants living with overweight or obesity Calcium supplementation for people with overweight or obesity (2024) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Morbidity · participants living with overweight or obesity Calcium supplementation for people with overweight or obesity (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs placebo Sexual quality of life · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs placebo Cardiovascular mortality · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs placebo Treatment withdrawal due to adverse events · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	RR 1.04 [0.58, 1.86]	2 studies · 122 participants	Very low
Testosterone vs placebo Prostate‐related events · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs placebo Lower urinary tract symptoms · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs PDE5I Erectile function · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	1 study · 64 participants	Very low
Testosterone vs PDE5I Sexual quality of life · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	1 study · 64 participants	Very low
Testosterone vs PDE5I Cardiovascular mortality · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies
Testosterone vs PDE5I Treatment withdrawal due to adverse events · men with sexual dysfunction Testosterone replacement in men with sexual dysfunction (2024) · Cochrane	no estimate extracted	NR	No studies