Cochrane · systematic review · CD008101

Continuous glucose monitoring systems for type 1 diabetes mellitus

Langendam, M, Luijf, YM, Hooft, L, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
11
No studies
2
Included studies
NR
No studies 2 · 14.3%Ungraded 1 · 7.1%Very low 7 · 50%Low 2 · 14.3%Moderate 2 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Continuous glucose monitoring (CGM) augmented pump therapy for type 1 diabetes mellitus in insulin pump naive patients

Population: patients with type 1 diabetes mellitus
7 questions
OutcomeEffectEvidenceStatus / GRADE
Diabetic complications
no estimate extractedNRNo studies
Severe hypoglycaemia
RR 3.26 [0.38, 27.82]1 study · 78 participantsVery low
Downgraded: imprecision
Ketoacidosis
RR 2.45 [0.1, 58.45]1 study · 78 participantsVery low
Downgraded: imprecision
Quality of life ‐ Various features
no estimate extracted5 studies · 412 participantsUngraded
Quality of life ‐ Physical health domain SF‐36 Short form
no estimate extracted1 study · 75 participantsVery low
Downgraded: imprecision
Quality of life ‐ Mental health domain SF‐36 Short form
no estimate extracted1 study · 75 participantsVery low
Downgraded: imprecision
Change in HbA1c (%)
no estimate extracted2 studies · 562 participantsModerate
Downgraded: imprecision, inconsistency

Continuous real‐time glucose monitoring (CGM) for type 1 diabetes mellitus

Population: patients with type 1 diabetes mellitus
7 questions
OutcomeEffectEvidenceStatus / GRADE
Diabetic complications
no estimate extractedNRNo studies
Severe hypoglycaemia
RR 1.05 [0.63, 1.77]5 studies · 689 participantsLow
Downgraded: imprecision
Ketoacidosis
RR 0.85 [0.32, 2.26]5 studies · 689 participantsLow
Downgraded: imprecision
Quality of life ‐ Physical health domain SF‐12
no estimate extracted1 study · 226 participantsVery low
Downgraded: imprecision, inconsistency
Quality of life ‐ Mental health domain SF‐12
no estimate extracted1 study · 226 participantsVery low
Downgraded: imprecision, inconsistency
Quality of life ‐ Parents SF‐12
no estimate extracted1 study · 226 participantsVery low
Downgraded: imprecision, inconsistency
Change in HbA1c (%)
no estimate extracted6 studies · 963 participantsModerate
Downgraded: imprecision, inconsistency