Non-Cochrane · intervention · PM42639523

The Contribution of the Self-adjusting File in Debris Removal in Root Canal Retreatment: A Systematic Review and Meta-analysis of in Vitro Studies.

El Abbassi Salma, Sakout Majid · Iranian endodontic journal · 2026 · PubMed · doi:10.22037/iej.v21i1.50916

Findings

4 findings

Population
Extracted mature permanent teeth undergoing endodontic retreatmentAdjunctive Self-adjusting File (SAF) after root canal filling removalRetreatment without supplementary SAF (conventional filling removal only)Residual root canal filling material (volume, micro-CT)
In vitro; extracted mature permanent teeth; micro-CT assessment · Full dataset (all canal morphologies)
SMD -0.50 [-0.82, -0.18]
GRADE not reported
5 studies
Extracted mature permanent teeth undergoing endodontic retreatment with oval canalsAdjunctive Self-adjusting File (SAF) after root canal filling removalRetreatment without supplementary SAF (conventional filling removal only)Residual root canal filling material (volume, micro-CT)
In vitro; extracted mature permanent teeth; micro-CT assessment · Oval canals
SMD -0.55 [-1.07, -0.02]
GRADE not reported
2 studies
Extracted mature permanent teeth undergoing endodontic retreatment with curved canalsAdjunctive Self-adjusting File (SAF) after root canal filling removalRetreatment without supplementary SAF (conventional filling removal only)Residual root canal filling material (volume, micro-CT)
In vitro; extracted mature permanent teeth; micro-CT assessment · Curved canals
SMD -0.27 [-0.68, 0.15]
GRADE not reported
2 studies
Extracted mature permanent teeth undergoing endodontic retreatment with severely curved canalsAdjunctive Self-adjusting File (SAF) after root canal filling removalRetreatment without supplementary SAF (conventional filling removal only)Residual root canal filling material (volume, micro-CT)
In vitro; extracted mature permanent teeth; micro-CT assessment · Severely curved canals
SMD -1.06 [-1.69, -0.43]
GRADE not reported
1 study

Included primary studies 28

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Aslan 2016
Degradation of benzenesulfonate to sulfite in bacterial extract.
PMID:201612
19772 other reviewsnot statednot extracted yet
Kumar 2020
matched by author and year (probable)
NR2 other reviewsnot statednot extracted yet
Abramovitz 2012
The effectiveness of a self‐adjusting file to remove residual gutta‐percha after retreatment with rotary files
DOI:10.1111/j.1365-2591.2011.01988.x
2012this review onlynot statednot extracted yet
Abramovitz 2012
The effectiveness of a self-adjusting file to remove residual gutta-percha after retreatment with rotary files.
PMID:22283664
2012this review onlynot statednot extracted yet
Alves 2012
EMC viral infection of the coronary blood vessels in newborn mice: viral vasculitis.
PMID:201264
1977this review onlynot statednot extracted yet
Aslan 2016
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Keles 2014
Oval-shaped canal retreatment with self-adjusting file: a micro-computed tomography study
DOI:10.1007/s00784-013-1086-0
2013this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Keles 2014 (flat-oval SEM)
Retreatment of flat-oval root canals with a self-adjusting file: an SEM study.
PMID:25311342
2014this review onlynot statednot extracted yet
Keles 2014 (oval canals micro-CT)
Oval-shaped canal retreatment with self-adjusting file: a micro-computed tomography study.
PMID:23959377
2014this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Keles 2014 (SEM)
Retreatment of flat-oval root canals with a self-adjusting file: An SEM study
DOI:10.4012/dmj.2014-054
2014this review onlynot statednot extracted yet
Keles 2016
The efficacy of laser, ultrasound and self‐adjustable file in removing smear layer debris from oval root canals following retreatment: A…
DOI:10.1111/aej.12145
2016this review onlynot statednot extracted yet
Keles 2016
The efficacy of laser, ultrasound and self-adjustable file in removing smear layer debris from oval root canals following retreatment: A…
PMID:26786709
2016this review onlynot statednot extracted yet
Kiraz 2023
Micro-CT evaluation of the removal of root fillings using rotary and reciprocating systems supplemented by XP-Endo Finisher, the…
PMID:38053777
2023this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Machado 2018
Effects of preparation with the Self‐Adjusting File, <scp>TRUS</scp>hape and <scp>XP</scp>‐endo Shaper systems, and a supplementary step…
DOI:10.1111/iej.13039
2018this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Machado 2018
Effects of preparation with the Self-Adjusting File, TRUShape and XP-endo Shaper systems, and a supplementary step with XP-endo Finisher R…
PMID:30417931
2019this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Pawar 2016
The efficacy of the Self-Adjusting File versus WaveOne in removal of root filling residue that remains in oval canals after the use of…
PMID:26957798
2016this review onlynot statednot extracted yet
Silva 2020
Comparison of the Self-Adjusting File and Hedström File Used as Supplementary Instruments for the Remaining Filling Material Removal…
DOI:10.14744/eej.2019-07-067
2020this review onlynot statednot extracted yet
Silva 2020
Comparison of the Self-Adjusting File and Hedström File Used as Supplementary Instruments for the Remaining Filling Material Removal…
PMID:32766520
2020this review onlynot statednot extracted yet
Simsek 2014
3D Analysis of D-RaCe and Self-Adjusting File in Removing Filling Materials from Curved Root Canals Instrumented and Filled with Different…
DOI:10.1155/2014/836513
2014this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Simsek 2014
3D analysis of D-RaCe and self-adjusting file in removing filling materials from curved root canals instrumented and filled with different…
PMID:25114976
2014this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Solomonov 2012
Self-Adjusting Files in Retreatment: A High-resolution Micro–Computed Tomography Study
DOI:10.1016/j.joen.2012.06.019
2012this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Solomonov 2012
Self-adjusting files in retreatment: a high-resolution micro-computed tomography study.
PMID:22892752
2012this review onlyResidual root canal filling material (volume, micro-CT)not extracted yet
Voet 2012
Removal of Gutta-percha from Root Canals Using the Self-Adjusting File
DOI:10.1016/j.joen.2012.03.003
2012this review onlynot statednot extracted yet
Voet 2012
Removal of gutta-percha from root canals using the self-adjusting file.
PMID:22703671
2012this review onlynot statednot extracted yet
Yuruker 2016
Efficacy of Combined Use of Different Nickel-Titanium Files on Removing Root Canal Filling Materials
DOI:10.1016/j.joen.2015.11.019
2016this review onlynot statednot extracted yet
Yuruker 2016
Efficacy of Combined Use of Different Nickel-Titanium Files on Removing Root Canal Filling Materials.
PMID:26778268
2016this review onlynot statednot extracted yet
Zhekov 2024
Differential expression of the tumor necrosis factor/cachectin gene by blood and lung mononuclear phagocytes.
PMID:3202418
1988this review onlynot statednot extracted yet
Zhekov 2024
Study on the Synthesis, Antioxidant Properties, and Self-Assembly of Carotenoid-Flavonoid Conjugates.
PMID:32024181
2020this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationExtracted mature permanent teethExtracted teeth with oval, curved or severely curved canals (16 studies; meta-analysis 5 studies)
InterventionAdditional use of the Self-adjusting File (SAF) after conventional root canal retreatmentAdjunctive SAF after filling removal (n=16)
ComparisonRetreatment without SAF; retreatment with an additional cleaning step with SAF (before/after within the same sample)Retreatment without SAF or with other supplementary methods (n=16)
OutcomesQuality of canal cleanliness (residual filling material) at the end of retreatment; meta-analysis on volume of residual filling by micro-CTResidual filling material volume by micro-CT (5 studies, 10 comparisons); other methods narrative
Study designsIn vitro studies on mature extracted permanent teeth requiring retreatmentIn vitro studies (n=16); risk of bias: 11 moderate, 5 low
TimingNot specifiedNot specified