Topic in Oral Health
Endodontics and dental trauma
Pulp and root canal treatment, periapical disease, and traumatized teeth.
25 systematic reviews in Endodontics and dental trauma ask 664 questions. 16.7% have no studies to answer them, 10.4% rest on very low certainty evidence and 2.6% reach moderate or high certainty.
Reviews
25
Questions
664
current versions
No studies
16.7%
Moderate or high
2.6%
No studies 111 · 16.7%Ungraded 417 · 62.8%Very low 69 · 10.4%Low 50 · 7.5%Moderate 16 · 2.4%High 1 · 0.2%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Partial pulpotomy vs Full (complete) pulpotomy Patient- and clinical-reported outcomes (tooth survival, clinical/radiographic success, pain) · Asymptomatic permanent teeth with deep caries (no symptoms) The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital… (2025) | no estimate extracted | 0 studies | No studies |
Intervention NR Tooth survival · - The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital… (2025) | no estimate extracted | 0 studies | No studies |
Partial pulpotomy vs Full (complete) pulpotomy Oral health-related quality of life (OHRQoL) · Mature permanent (molar) teeth with deep caries and symptoms indicative of irreversible pulpitis (spontaneous pain) · >=6 months The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital… (2025) | no estimate extracted | 0 studies | No studies |
Partial pulpotomy vs Full (complete) pulpotomy Patient- and clinical-reported outcomes (tooth survival, clinical/radiographic success, pain) · Permanent teeth with deep caries and reversible pulpitis (non-spontaneous pain) The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital… (2025) | no estimate extracted | 0 studies | No studies |
Pulpotomy (full or partial) vs None (single-arm success proportion) Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · >=12 months Efficacy of pulpotomy for permanent teeth with carious pulp exposure: A systematic review and meta-analysis… (2024) | Proportion 0.867 [0.820, 0.907] | 25 studies · 2012 participants | Very low |
Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) Clinical and radiographic success (composite) · Patients with carious pulp exposure in immature permanent teeth · ≥6 months; follow-up range 1-2 years, Root maturation: immature Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious… (2023) | OR 2.22 [0.13, 36.67] | 2 studies · 106 participants | Very low |
Calcium hydroxide (CH) vs Mineral trioxide aggregate (MTA) Clinical and radiographic success (composite) · Patients with carious pulp exposure in permanent teeth of mixed/unspecified root maturation · ≥6 months; follow-up range 1-2 years, Root maturation: mixed Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious… (2023) | OR 1.11 [0.17, 7.11] | 3 studies · 257 participants | Very low |
Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH) Clinical and radiographic success · Patients with carious pulp exposure in immature permanent teeth · 1 to 2 years, Immature teeth Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious… (2023) | OR 2.22 [0.13, 36.67] | 2 studies · 106 participants | Very low |
Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH) Clinical and radiographic success · Patients with carious pulp exposure in permanent teeth with mixed root development · 1 to 2 years, Mixed root development Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious… (2023) | OR 1.11 [0.17, 7.11] | 3 studies · 257 participants | Very low |
Pulpotomy (partial or full) vs None (single-arm pooled success proportion) Clinical and radiographic success rate (>=6 months) · Human permanent teeth with irreversible pulpitis (symptomatic and asymptomatic) due to carious pulp exposure · >=6 months, Observational studies (GRADE evidence profile) Outcome of pulpotomy in permanent teeth with irreversible pulpitis: a systematic review and meta-analysis. (2022) | Proportion 0.926 [0.86, 0.96] | 6 studies · 177 participants | Very low |
Pulpotomy (partial or full) vs None (single-arm pooled success proportion) Clinical and radiographic success rate (>=6 months) · Human permanent teeth with irreversible pulpitis (symptomatic and asymptomatic) due to carious pulp exposure · >=6 months, Randomized trials (GRADE evidence profile) Outcome of pulpotomy in permanent teeth with irreversible pulpitis: a systematic review and meta-analysis. (2022) | Proportion 0.743 [0.56, 0.86] | 5 studies · 488 participants | Very low |
Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits) Tooth extraction due to endodontic problems · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without… Single versus multiple visits for endodontic treatment of permanent teeth (2022) · Cochrane | RR 0.46 [0.09, 2.50] | 2 studies · 402 participants | Very low |
Reviews 25
The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital permanent teeth with a diagnosis of non-traumatic pulpitis.
Non-Cochranefull textintervention2 included studies
9 questions
Effectiveness of calcium hydroxide compared to hydraulic calcium silicate cements for direct pulp capping in managing deep caries in vital permanent teeth: A systematic review and meta-analysis.
Non-Cochranefull textintervention9 included studies
6 questions
Partial pulpotomy for carious pulp exposure in adult mature permanent teeth: a systematic review and meta-analysis.
Non-Cochranefull textintervention11 included studies
18 questions
Efficacy of pulpotomy for permanent teeth with carious pulp exposure: A systematic review and meta-analysis of randomized controlled trials.
Non-Cochranefull textintervention25 included studies
39 questions
Incidence and influential factors in pulp necrosis and periapical pathosis following indirect restorations: a systematic review and meta-analysis.
Non-Cochranefull textprognostic68 included studies
57 questions
Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious teeth: A systematic review and meta-analysis.
Non-Cochranefull textintervention21 included studies
19 questions
Single versus multiple visits for endodontic treatment of permanent teeth
Cochranefull textintervention
12 questions
Clinical effectiveness of restorative materials for the restoration of carious primary teeth without pulp therapy: a systematic review.
Non-Cochranefull textintervention53 included studies
46 questions
Clinical effectiveness of restorative materials for the restoration of carious lesions in pulp treated primary teeth: a systematic review.
Non-Cochranefull textintervention5 included studies
16 questions
Outcome of pulpotomy in permanent teeth with irreversible pulpitis: a systematic review and meta-analysis.
Non-Cochranefull textintervention11 included studies
14 questions
Materials for retrograde filling in root canal therapy
Cochranefull textintervention
16 questions
Antibiotic use for irreversible pulpitis
Cochranefull textintervention
5 questions
Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted
Cochranefull textintervention
18 questions
Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis.
Non-Cochranefull textintervention5 included studies
11 questions
Pulp treatment for extensive decay in primary teeth
Cochranefull textintervention
220 questions
Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review and meta-analysis.
Non-Cochranefull textintervention4 included studies
11 questions
Endodontic procedures for retreatment of periapical lesions
Cochranefull textintervention
33 questions
Magnification devices for endodontic therapy
Cochranefull textintervention
12 questions
Interventions for treating traumatised ankylosed permanent front teeth
Cochranefull textintervention
4 questions
Interventions for the management of external root resorption
Cochranefull textintervention
1 questions
Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth
Cochranefull textintervention
4 questions
Irrigants for non‐surgical root canal treatment in mature permanent teeth
Cochranefull textintervention
70 questions
Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth
Cochranefull textintervention
2 questions
Pulp management for caries in adults: maintaining pulp vitality
Cochranefull textintervention
15 questions
Root canal posts for the restoration of root filled teeth
Cochranefull textintervention
6 questions